Protein: GPAT4
Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7)

Gene: GPAT4
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q86UL3

Gene Ontology (top 5):
GO:0002071 - glandular epithelial cell maturation
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0004366 - glycerol-3-phosphate O-acyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1288651

CHP1
Calcineurin B homologous protein 1

3

3

High-throughput

0.643

High

248900

GSDME
Gasdermin-E

2

2

High-throughput

0.628

High

1288672

EHD2
EH domain-containing protein 2

2

1

High-throughput

0.628

High

1288679

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

3

High-throughput

0.601

High

951236

SC61B
Protein transport protein Sec61 subunit beta

2

3

High-throughput

0.584

High

1288644

TSN17
Tetraspanin-17

2

15

High-throughput

0.558

High

942499

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

2

High-throughput

0.541

High

62140

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

13

High-throughput

0.536

High

125027

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

182635

GP182
G-protein coupled receptor 182

1

16

High-throughput

0.536

High

380450

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

4

High-throughput

0.536

High

565653

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

12

High-throughput

0.536

High

574104

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

5

High-throughput

0.536

High

669020

FPR2
N-formyl peptide receptor 2

1

12

High-throughput

0.536

High

845067

EAA3
Excitatory amino acid transporter 3

1

3

High-throughput

0.536

High

1213638

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

3

High-throughput

0.536

High

1288627

LRC25
Leucine-rich repeat-containing protein 25

1

1

High-throughput

0.536

High

1288628

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

3

High-throughput

0.536

High

1288634

SPP2B
Signal peptide peptidase-like 2B

1

1

High-throughput

0.536

High

1288637

AQP3
Aquaporin-3

1

3

High-throughput

0.536

High

1288640

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

9

High-throughput

0.536

High

1288643

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.536

High

1288652

CML1
Chemerin-like receptor 1

1

9

High-throughput

0.536

High

1288661

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.536

High

1288663

SG196
Protein O-mannose kinase

1

3

High-throughput

0.536

High

1288678

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.536

High

1288682

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

High-throughput

0.536

High

162224

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.513

High

344471

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

1245871

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

1288632

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

1288645

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

165977

FFAR1
Free fatty acid receptor 1

1

9

High-throughput

0.489

High

260901

RAMP3
Receptor activity-modifying protein 3

1

6

High-throughput

0.489

High

349466

TSN15
Tetraspanin-15

1

14

High-throughput

0.489

High

469509

SYPH
Synaptophysin

1

1

High-throughput

0.489

High

575673

GPIX
Platelet glycoprotein IX

1

4

High-throughput

0.489

High

618395

TSN8
Tetraspanin-8

1

13

High-throughput

0.489

High

638210

S1PR1
Sphingosine 1-phosphate receptor 1

1

5

High-throughput

0.489

High

733011

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

5

High-throughput

0.489

High

771165

APJ
Apelin receptor

1

6

High-throughput

0.489

High

835316

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

5

High-throughput

0.489

High

1098914

KLRD1
Natural killer cells antigen CD94

1

10

High-throughput

0.489

High

1251663

T184A
Transmembrane protein 184A

1

1

High-throughput

0.489

High

1288622

ST32C
Serine/threonine-protein kinase 32C

1

3

High-throughput

0.489

High

1288623

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.489

High

1288625

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1288635

HUMMR
Protein MGARP

1

1

High-throughput

0.489

High

1288639

LPAR1
Lysophosphatidic acid receptor 1

1

7

High-throughput

0.489

High

1288648

OPALI
Opalin

1

2

High-throughput

0.489

High

1288654

FEM1A
Protein fem-1 homolog A

1

3

High-throughput

0.489

High

1288657

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

2

High-throughput

0.489

High

1288666

GPR35
G-protein coupled receptor 35

1

7

High-throughput

0.489

High

1288681

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.489

High

48681

ESYT2
Extended synaptotagmin-2

1

6

High-throughput

0.479

High

173977

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

9

High-throughput

0.479

High

414126

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

417543

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

4

High-throughput

0.479

High

418242

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.479

High

466333

RHOC
Rho-related GTP-binding protein RhoC

1

14

High-throughput

0.479

High

540535

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

581144

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.479

High

611204

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

634507

LMNB1
Lamin-B1

1

2

High-throughput

0.479

High

698833

CALX
Calnexin

1

4

High-throughput

0.479

High

715650

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.479

High

820679

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.479

High

847582

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.479

High

894865

EMD
Emerin

1

2

High-throughput

0.479

High

903985

BAP31
B-cell receptor-associated protein 31

1

5

High-throughput

0.479

High

953536

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.479

High

955335

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.479

High

962224

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

1015567

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

1027061

REEP5
Receptor expression-enhancing protein 5

1

3

High-throughput

0.479

High

1058495

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

1087168

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1111590

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

1163367

CAH9
Carbonic anhydrase 9

1

3

High-throughput

0.479

High

1287360

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

High-throughput

0.479

High

1288621

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

1

High-throughput

0.479

High

1288630

DHB11
Estradiol 17-beta-dehydrogenase 11

1

9

High-throughput

0.479

High

1288636

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.479

High

1288641

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

6

High-throughput

0.479

High

1288642

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1288649

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1288650

SEC62
Translocation protein SEC62

1

5

High-throughput

0.479

High

1288653

ESYT1
Extended synaptotagmin-1

1

6

High-throughput

0.479

High

1288655

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1288656

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.479

High

1288658

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1288659

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.479

High

1288664

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1288667

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

1288668

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

1288671

ELOV5
Very long chain fatty acid elongase 5

1

3

High-throughput

0.479

High

1288673

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

1288674

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1288680

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

6

High-throughput

0.479

High

1203066

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

380086

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

869614

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

10

High-throughput

0.445

High

880847

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.445

High

1139481

S39AE
Metal cation symporter ZIP14

1

14

High-throughput

0.445

High

1251147

ZNT10
Calcium/manganese antiporter SLC30A10

1

4

High-throughput

0.445

High

1288631

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.445

High

1288660

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

10

High-throughput

0.445

High

1217737

GFI1B
Zinc finger protein Gfi-1b

1

1

High-throughput

0.439

High

49665

T120B
Transmembrane protein 120B

1

1

High-throughput

0.437

High

126673

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.437

High

218400

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

293947

CD123
Translation initiation factor eIF2 assembly protein

1

5

High-throughput

0.437

High

302877

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.437

High

768555

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

900891

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.437

High

901359

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.437

High

910114

RND2
Rho-related GTP-binding protein RhoN

1

18

High-throughput

0.437

High

913350

MSH6
DNA mismatch repair protein Msh6

1

1

High-throughput

0.437

High

1004780

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1238724

TECT3
Tectonic-3

1

6

High-throughput

0.437

High

1254459

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1288624

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1288626

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

1288646

TECT2
Tectonic-2

1

6

High-throughput

0.437

High

1288662

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

1288665

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.437

High

1288670

OTULL
Inactive ubiquitin thioesterase OTULINL

1

6

High-throughput

0.437

High

1288675

TES
Testin

1

1

High-throughput

0.437

High

1288677

XPO7
Exportin-7

1

2

High-throughput

0.437

High

652209

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

5

High-throughput

0.407

High

1242840

S39A4
Zinc transporter ZIP4

1

14

High-throughput

0.407

High

1288629

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.407

High

1288633

ZNT7
Zinc transporter 7

1

4

High-throughput

0.407

High

1288638

YLAT2
Y+L amino acid transporter 2

1

5

High-throughput

0.407

High

749226

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

1288669

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.279

Low

1288647

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1288676

NCKX2
Sodium/potassium/calcium exchanger 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025