HitPredict

Interactor 1: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 716 Hs			1 1190
+	Ce
		873625 MIG5_CAEEL (2-545): 2.14e-57: 208: 26.29		LIN2_CAEEL (212-890): 1.23e-94: 327: 14.79
+	Hs
		151114 DVL2_HUMAN (3-716): 2.33e-133: 412: 65.13		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Mm
		251104 DLG1_MOUSE (87-686): 4e-44: 172: 14.79		CSKP_MOUSE (229-890): 6.48e-93: 321: 15.09
+	Hs
		159200 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Mm
		1143555 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		MPP2_MOUSE (426-888): 3.06e-95: 317: 16.15
+	Hs
		1021489 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		MPP2_HUMAN (428-890): 1.51e-90: 305: 16.35
+	Dm
		677684 DSH_DROME (3-558): 5.64e-101: 324: 46.13		DLG1_DROME (12-421): 3.86e-35: 147: 17.36
+	Ce
		105565 Q18239_CAEEL (4-626): 4.09e-89: 297: 31.14		DLG1_CAEEL (339-611): 2.49e-14: 80.2: 14.98
+	Mm
		1143387 DLG1_MOUSE (87-686): 4e-44: 172: 14.79		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1113136 Q3UP61_MOUSE (113-686): 3.54e-43: 169: 14.43		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143321 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		1021482 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		1021501 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		DLG2_HUMAN (8-518): 4.46e-45: 178: 15.49
+	Mm
		1143467 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		DLG2_MOUSE (8-534): 5.21e-45: 178: 15.58
+	Ce
		105570 MIG5_CAEEL (2-545): 2.14e-57: 208: 26.29		DLG1_CAEEL (339-611): 2.49e-14: 80.2: 14.98
+	Hs
		1021542 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61
+	Mm
		1119795 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		Q52KF7_MOUSE (2-318): 5.84e-23: 107: 16.61
+	Mm
		936180 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		DLG3_MOUSE (372-595): 5.97e-13: 75.5: 18.10