Protein: PIWI
Protein piwi (EC 3.1.26.-) (Protein P-element induced wimpy testis)

Gene: PIWI
Organism: Drosophila melanogaster
Interactions: 62
UniProt ID: Q9VKM1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000792 - heterochromatin
GO:0003723 - RNA binding
GO:0004521 - RNA endonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1235283

ARMI
Probable RNA helicase armi

6

12

Small-scale

0.729

High

1479675

PANX
Protein panoramix

5

0

Small-scale

0.676

High

1479666

TDRKH
Tudor and KH domain-containing protein homolog

2

20

Small-scale

0.661

High

1343462

ASTRX
Gametocyte-specific factor 1 homolog

4

0

Small-scale

0.648

High

426783

HP1
Heterochromatin protein 1

3

0

Small-scale

0.646

High

1470788

DCR1
Endoribonuclease Dcr-1

1

20

Small-scale

0.618

High

1470764

VRET
Protein vreteno

2

2

Small-scale

0.611

High

1445532

FMR1
Fragile X messenger ribonucleoprotein 1 homolog

2

17

Small-scale

0.584

High

1477450

MUT7
Exonuclease mut-7 homolog

2

1

Small-scale

0.584

High

1479667

NXF2
Nuclear RNA export factor 2

2

0

Small-scale

0.559

High

1479676

Q9XYM5
LD27861p

2

0

Small-scale

0.559

High

1475657

Q9VH81
protein-serine/threonine phosphatase

1

5

High-throughput

0.484

High

95518

E2QCN4
Not1, isoform F

1

2

Small-scale

0.479

High

356873

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

1

Small-scale

0.479

High

391917

HSP83
Heat shock protein 83

1

20

Small-scale

0.479

High

654362

DDX6
ATP-dependent RNA helicase me31b

1

20

High-throughput

0.479

High

837333

EZ
Histone-lysine N-methyltransferase E(z)

1

3

Small-scale

0.479

High

1069312

Q0E8J0
MOG interacting and ectopic P-granules protein 1

1

1

Small-scale

0.479

High

1173882

ESC
Polycomb protein esc

1

4

Small-scale

0.479

High

1174385

CP190
Centrosome-associated zinc finger protein Cp190

1

3

Small-scale

0.479

High

1175612

CAF1
Chromatin assembly factor 1 p55 subunit

1

2

Small-scale

0.479

High

1264595

Q7K112
poly(A)-specific ribonuclease

1

7

Small-scale

0.479

High

1269146

Q7KT57
HDC02844

1

1

Small-scale

0.479

High

1374483

HDAC1
Histone deacetylase HDAC1

1

6

Small-scale

0.479

High

1379169

KI10A
Kinesin-like protein Klp10A

1

2

Small-scale

0.479

High

1463638

NXT1
NTF2-related export protein

1

4

Small-scale

0.479

High

1472309

Q9VE55
Qin

1

20

Small-scale

0.479

High

1479471

ZUC
Mitochondrial cardiolipin hydrolase

1

2

Small-scale

0.479

High

1479665

Q9VPN5
Stress-induced-phosphoprotein 1

1

12

Small-scale

0.479

High

1479671

SND1
Staphylococcal nuclease domain-containing protein 1

1

20

Small-scale

0.479

High

1479674

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase shutdown

1

16

Small-scale

0.479

High

380861

H1
Histone H1

1

0

Small-scale

0.458

High

831805

CORTO
Centrosomal and chromosomal factor

1

0

Small-scale

0.458

High

1264809

HENMT
Small RNA 2'-O-methyltransferase

1

0

Small-scale

0.458

High

1445692

SUZ12
Polycomb protein Su(z)12

1

0

Small-scale

0.458

High

1457971

XMAS
Protein xmas

1

0

Small-scale

0.458

High

1465462

Q9V455
Importin subunit alpha

1

0

Small-scale

0.458

High

1479668

LSDA
Possible lysine-specific histone demethylase 1

1

0

Small-scale

0.458

High

1479669

ELYS
Protein ELYS homolog

1

0

Small-scale

0.458

High

1479673

THOC5
THO complex subunit 5

1

0

Small-scale

0.458

High

458052

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

6

High-throughput

0.445

High

757084

FAS2
Fasciclin-2

1

1

High-throughput

0.445

High

852519

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.445

High

877818

RB27C
Heterogeneous nuclear ribonucleoprotein 27C

1

17

High-throughput

0.445

High

1064239

SQD
RNA-binding protein squid

1

17

High-throughput

0.445

High

1321410

SHEP
Protein alan shepard

1

20

High-throughput

0.445

High

1471829

MED25
Mediator of RNA polymerase II transcription subunit 25

1

3

High-throughput

0.445

High

82039

VASA2
Sister chromatid cohesion protein solo

1

1

Small-scale

0.437

High

1377438

Q95RF6
LD34461p

1

2

High-throughput

0.437

High

1305029

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.426

High

1374573

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

1479663

Q9VMM7
FI04466p

1

0

High-throughput

0.426

High

1479664

Q9VP57
LD15904p

1

0

High-throughput

0.426

High

1267645

Q7KMM5
BcDNA.GH04802

1

1

High-throughput

0.407

High

1320763

Q8MLV8
Peptidase S1 domain-containing protein

1

1

High-throughput

0.407

High

1374894

ORK1
Open rectifier potassium channel protein 1

1

1

High-throughput

0.407

High

1479672

Q9W174
trypsin

1

1

High-throughput

0.407

High

1014810

H4
Histone H4

1

0

High-throughput

0.232

Low

1175244

NETB
Netrin-B

1

0

High-throughput

0.232

Low

1269879

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.232

Low

1445340

VATD2
V-type proton ATPase subunit D 2

1

0

High-throughput

0.232

Low

1479670

Q9VWF7
Phosphoseryl tRNA kinase, isoform A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025