HitPredict

Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1102 Hs			1 350
+	Hs
		718079 UBP7_HUMAN (1-1102): 0: 1165: 100.00		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		718415 UBP7_HUMAN (1-1102): 0: 1165: 100.00		PCGF2_HUMAN (117-350): 6.32e-65: 211: 33.47
+	Hs
		1108527 UBP7_HUMAN (1-1102): 0: 1165: 100.00		PCGF3_HUMAN (120-341): 3.31e-65: 208: 34.44
+	Hs
		1273836 UBP7_HUMAN (1-1102): 0: 1165: 100.00		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		1273786 UBP7_HUMAN (1-1102): 0: 1165: 100.00		CHFR_HUMAN (2-264): 1.21e-37: 144: 17.61
+	Hs
		1223388 UBP7_HUMAN (1-1102): 0: 1165: 100.00		TRI22_HUMAN (127-312): 3.27e-35: 135: 12.92
+	Hs
		1273821 UBP7_HUMAN (1-1102): 0: 1165: 100.00		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Mm
		1149466 UBP7_MOUSE (1-1102): 0: 1159: 99.00		RING2_MOUSE (85-303): 2.38e-32: 125: 14.49
+	Hs
		988002 UBP7_HUMAN (1-1102): 0: 1165: 100.00		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Hs
		718324 UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		1173873 UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		1273718 USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		1311542 UBP42_HUMAN (162-683): 1.67e-95: 334: 18.44		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		1019375 UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13		TRI26_HUMAN (121-315): 1.51e-31: 126: 19.90