HitPredict

Interactor 1: MED12 (Q93074)
Mediator of RNA polymerase II transcription subunit 12 (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (Mediator complex subunit 12) (OPA-containing protein) (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Trinucleotide repeat-containing gene 11 protein)
Gene: MED12

Interactor 2: MED29 (Q9NX70)
Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
Gene: MED29

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	15175163, 33961781, 35271311, 15989967, 26496610, 24981860, 20133760
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016592 - mediator complex GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 2177 Hs			1 200
+	Hs
		1206164 MD12L_HUMAN (1-2175): 0: 2159: 56.63		MED29_HUMAN (1-200): 1.12e-108: 311: 100.00