Interactor 1: RPOM (O00411)
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)
Gene: POLRMT

Interactor 2: TFB1M (Q8WVM0)
Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)
Gene: TFB1M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 12897151
Identification Methods affinity chromatography technology, immunodepleted coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RPOL_N~RrnaAD
Common GO terms GO:0003723 - RNA binding
GO:0005759 - mitochondrial matrix
GO:0006391 - transcription initiation at mitochondrial promoter
GO:0034245 - mitochondrial DNA-directed RNA polymerase complex
GO:0042645 - mitochondrial nucleoid
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1230
Hs

1 346
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024