HitPredict

Interactor 1: MOB1 (Q95RA8)
MOB kinase activator-like 1 (Mob as tumor suppressor protein 1) (Dmob1) (Mps one binder kinase activator-like 1)
Gene: mats

Interactor 2: TRC (Q9NBK5)
Serine/threonine-protein kinase tricornered (EC 2.7.11.1) (NDR protein kinase) (Serine/threonine-protein kinase 38-like) (Serine/threonine-protein kinase tricorner)
Gene: TRC

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Dm			1 463
+	Hs
		1185506 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		ST38L_HUMAN (17-460): 3.3e-169: 485: 70.50
+	Hs
		1333714 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		ST38L_HUMAN (17-460): 3.3e-169: 485: 70.50
+	Hs
		1069623 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		STK38_HUMAN (14-460): 3.46e-165: 475: 68.89
+	Hs
		1069652 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		STK38_HUMAN (14-460): 3.46e-165: 475: 68.89
+	Hs
		1185503 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		LATS2_HUMAN (9-457): 1.06e-148: 453: 41.90
+	Hs
		325787 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		LATS1_HUMAN (9-457): 2.57e-148: 453: 39.66
+	Hs
		1333705 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		LATS2_HUMAN (9-457): 1.06e-148: 453: 41.90
+	Hs
		325891 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		LATS1_HUMAN (9-457): 2.57e-148: 453: 39.66
+	Dm
		1278870 MOB1_DROME (1-219): 4.13e-114: 326: 100.00		WARTS_DROME (18-451): 6.37e-144: 441: 43.71
+	Dm
		1099222 MOB1_DROME (1-219): 4.13e-114: 326: 100.00		Q24590_DROME (18-451): 9.61e-144: 440: 43.71
+	Hs
		1198336 MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11		LATS2_HUMAN (9-457): 1.06e-148: 453: 41.90
+	Hs
		325791 MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11		LATS1_HUMAN (9-457): 2.57e-148: 453: 39.66
+	Hs
		1285989 MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24		LATS2_HUMAN (9-457): 1.06e-148: 453: 41.90
+	Hs
		325844 MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24		LATS1_HUMAN (9-457): 2.57e-148: 453: 39.66
+	Hs
		1174306 MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41		LATS2_HUMAN (9-457): 1.06e-148: 453: 41.90
+	Hs
		325785 MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41		LATS1_HUMAN (9-457): 2.57e-148: 453: 39.66
+	Ca
		1124241 MOB2_CANAL (25-215): 3.4e-85: 256: 39.27		CBK1_CANAL (17-460): 1.4e-160: 473: 47.87
+	Sp
		140739 MOB2_SCHPO (14-216): 2.75e-85: 254: 38.92		ORB6_SCHPO (17-462): 7.21e-164: 472: 48.34
+	Sp
		293187 MOB1_SCHPO (3-212): 2.16e-98: 286: 54.76		SID2_SCHPO (3-456): 6.77e-131: 393: 29.94
+	Sc
		605543 MOB1_YEAST (2-212): 1.05e-83: 253: 50.47		DBF2_YEAST (2-456): 2.71e-128: 385: 28.66