HitPredict

Interactor 1: MOB1 (Q95RA8)
MOB kinase activator-like 1 (Mob as tumor suppressor protein 1) (Dmob1) (Mps one binder kinase activator-like 1)
Gene: mats

Interactor 2: WARTS (Q9VA38)
Serine/threonine-protein kinase Warts (EC 2.7.11.1)
Gene: wts

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	15766530, 24114784, 19913529, 24012335, 17347649
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation GO:0035329 - hippo signaling GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Dm			1 1105
+	Dm
		1099222 MOB1_DROME (1-219): 4.13e-114: 326: 100.00		Q24590_DROME (1-1105): 0: 849: 99.28
+	Hs
		1185503 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		LATS2_HUMAN (117-1101): 0: 570: 39.52
+	Hs
		1333705 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		LATS2_HUMAN (117-1101): 0: 570: 39.52
+	Hs
		1198336 MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11		LATS2_HUMAN (117-1101): 0: 570: 39.52
+	Hs
		1285989 MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24		LATS2_HUMAN (117-1101): 0: 570: 39.52
+	Hs
		1174306 MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41		LATS2_HUMAN (117-1101): 0: 570: 39.52
+	Hs
		325787 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59
+	Hs
		325891 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59
+	Hs
		325791 MOB3B_HUMAN (5-212): 5.26e-107: 308: 53.11		LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59
+	Hs
		325844 MOB3A_HUMAN (5-212): 9.77e-105: 302: 50.24		LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59
+	Hs
		325785 MOB3C_HUMAN (5-212): 1.99e-104: 301: 46.41		LATS1_HUMAN (180-1100): 2.27e-168: 528: 42.59
+	Dm
		1278869 MOB1_DROME (1-219): 4.13e-114: 326: 100.00		TRC_DROME (629-1091): 3.06e-154: 469: 41.08
+	Hs
		1185506 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		ST38L_HUMAN (643-1089): 3.23e-154: 469: 42.86
+	Hs
		1069623 MOB1B_HUMAN (1-215): 2.98e-113: 324: 88.37		STK38_HUMAN (643-1089): 4.96e-154: 468: 43.75
+	Hs
		1333714 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		ST38L_HUMAN (643-1089): 3.23e-154: 469: 42.86
+	Hs
		1069652 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		STK38_HUMAN (643-1089): 4.96e-154: 468: 43.75
+	Hs
		117030 MOB1A_HUMAN (1-215): 1.12e-112: 322: 86.51		SGK1_HUMAN (666-1090): 4.02e-134: 415: 28.87
+	Sp
		140739 MOB2_SCHPO (14-216): 2.75e-85: 254: 38.92		ORB6_SCHPO (639-1087): 8.6e-158: 478: 39.82
+	Ca
		1124241 MOB2_CANAL (25-215): 3.4e-85: 256: 39.27		CBK1_CANAL (463-1088): 2.84e-152: 473: 30.86
+	Sp
		293187 MOB1_SCHPO (3-212): 2.16e-98: 286: 54.76		SID2_SCHPO (551-1086): 1.26e-134: 423: 27.72