HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38580884, 23443559
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 393
+	Hs
		387631 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		175931 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		P73_HUMAN (13-362): 2.35e-166: 481: 39.74
+	Hs
		1330005 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		P63_HUMAN (28-363): 2.35e-145: 429: 42.11
+	Hs
		386781 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		387257 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		386661 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		387237 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		385994 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		P53_HUMAN (1-393): 0: 619: 100.00
+	Dm
		112944 M9NF14_DROME (3-478): 3.22e-17: 87.3: 16.07		Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31