Protein: PSME4
Proteasome activator complex subunit 4 (Proteasome activator PA200)

Gene: PSME4
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q14997

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637420

PSA1
Proteasome subunit alpha type-1

4

5

High-throughput

0.903

High

1061392

PSB7
Proteasome subunit beta type-7

4

9

High-throughput

0.903

High

832103

PSB2
Proteasome subunit beta type-2

4

11

Small-scale

0.900

High

656463

PSB4
Proteasome subunit beta type-4

4

12

High-throughput

0.895

High

594529

PSB1
Proteasome subunit beta type-1

3

13

High-throughput

0.871

High

831991

PSB3
Proteasome subunit beta type-3

3

11

High-throughput

0.871

High

637689

PSA2
Proteasome subunit alpha type-2

3

8

Small-scale

0.861

High

656115

PSB9
Proteasome subunit beta type-9

3

10

High-throughput

0.861

High

156290

PSA7
Proteasome subunit alpha type-7

2

5

High-throughput

0.811

High

638132

PSA4
Proteasome subunit alpha type-4

2

8

High-throughput

0.811

High

656228

PSA5
Proteasome subunit alpha type-5

2

6

High-throughput

0.811

High

656716

PSB5
Proteasome subunit beta type-5

2

11

High-throughput

0.811

High

637883

PSA3
Proteasome subunit alpha type-3

1

7

High-throughput

0.691

High

656062

PSB8
Proteasome subunit beta type-8

1

11

High-throughput

0.691

High

656600

PSB6
Proteasome subunit beta type-6

1

12

High-throughput

0.691

High

893671

PSA6
Proteasome subunit alpha type-6

1

8

High-throughput

0.691

High

130892

PSDE
26S proteasome non-ATPase regulatory subunit 14

3

2

Small-scale

0.640

High

1061376

PSME4
Proteasome activator complex subunit 4

1

1

High-throughput

0.618

High

913267

PRS10
26S proteasome regulatory subunit 10B

2

6

Small-scale

0.611

High

536625

FPPS
Farnesyl pyrophosphate synthase

2

0

High-throughput

0.602

High

1061394

SLX1
Structure-specific endonuclease subunit SLX1

2

0

High-throughput

0.602

High

346812

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.585

High

874097

PSMD4
26S proteasome non-ATPase regulatory subunit 4

2

0

High-throughput

0.585

High

1061400

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

2

0

Small-scale

0.585

High

983126

UBE3A
Ubiquitin-protein ligase E3A

2

1

Small-scale

0.584

High

917285

H4
Histone H4

2

0

Small-scale

0.582

High

893552

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.576

High

108944

H0YKT8
Proteasome subunit beta

1

8

High-throughput

0.575

High

1025390

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.549

High

1061386

NUTM1
NUT family member 1

1

0

High-throughput

0.549

High

121760

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

2

High-throughput

0.536

High

122015

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

2

High-throughput

0.536

High

572955

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.536

High

730262

PRS7
26S proteasome regulatory subunit 7

1

5

High-throughput

0.536

High

798665

PRS6B
26S proteasome regulatory subunit 6B

1

4

High-throughput

0.536

High

906830

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.536

High

907029

PRS8
26S proteasome regulatory subunit 8

1

6

High-throughput

0.536

High

1027651

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

4

High-throughput

0.536

High

1061377

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.536

High

1061389

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

1061393

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.536

High

1061399

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.536

High

198627

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.513

High

314758

PSMG1
Proteasome assembly chaperone 1

1

0

High-throughput

0.513

High

678880

HXA13
Homeobox protein Hox-A13

1

0

High-throughput

0.513

High

986797

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1061380

KYNU
Kynureninase

1

0

High-throughput

0.513

High

1061383

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.513

High

1061390

ISL2
Insulin gene enhancer protein ISL-2

1

0

High-throughput

0.513

High

1061397

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.513

High

1061398

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.513

High

1061378

UBE3C
Ubiquitin-protein ligase E3C

1

1

High-throughput

0.489

High

791566

HD
Huntingtin

1

0

Small-scale

0.480

High

227478

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

872157

RD23A
UV excision repair protein RAD23 homolog A

1

1

Small-scale

0.479

High

1061395

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

299375

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

651228

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

720490

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

1026413

RFA4
Replication protein A 30 kDa subunit

1

0

High-throughput

0.458

High

1035438

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1042991

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1061379

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

High-throughput

0.458

High

1061396

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

705

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.445

High

255151

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.426

High

402023

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

92621

E9PMD8
Proteasome 26S subunit, ATPase 3

1

6

High-throughput

0.407

High

380209

A1BG
Alpha-1B-glycoprotein

2

0

High-throughput

0.328

High

1061381

TAF7L
Transcription initiation factor TFIID subunit 7-like

2

0

High-throughput

0.328

High

1061382

KLH10
Kelch-like protein 10

2

0

High-throughput

0.328

High

445943

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.279

Low

506301

MBL2
Mannose-binding protein C

1

0

High-throughput

0.279

Low

672670

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1061387

MUT7
Exonuclease mut-7 homolog

1

0

High-throughput

0.279

Low

1061388

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.279

Low

1061391

TMCO6
Transmembrane and coiled-coil domain-containing protein 6

1

0

High-throughput

0.279

Low

815879

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.265

Low

384857

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1061384

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1061385

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024