HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35031058, 17643375
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0051028 - mRNA transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 372
+	Hs
		128025 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		128079 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		453668 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		162175 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		610081 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		852190 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		128159 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		1306035 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		128165 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		1020343 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		1048259 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Xl
		251135 IF23A_XENLA (1-579): 1.82e-136: 411: 77.44		Q6GM69_XENLA (2-99): 7.67e-17: 82.5: 30.61
+	Hs
		1288222 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		MSI2H_HUMAN (2-91): 6.69e-16: 79.8: 35.56
+	Hs
		1031481 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		453374 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		609880 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		1016053 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		Q12771_HUMAN (2-223): 3.47e-56: 187: 36.04
+	Hs
		852064 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		1048069 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Mm
		857294 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		TIA1_MOUSE (99-193): 5.17e-09: 59.4: 17.71