HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 758
+	Hs
		497692 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498054 Q62029_MOUSE (1-505): 3.11e-65: 226: 12.34		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		497064 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497407 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497065 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496957 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		497959 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		497393 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496179 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498053 PCBP2_MOUSE (193-484): 2.7e-30: 123: 21.16		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		496596 NOVA1_HUMAN (279-477): 8.23e-10: 63.5: 27.72		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582032 PABP1_RAT (74-346): 8.62e-12: 70: 8.30		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94258 PABP1_RAT (74-346): 8.62e-12: 70: 8.30		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		497957 PCBP3_MOUSE (134-273): 5.4e-10: 63.3: 20.71		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		653982 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		1056922 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		1056915 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		516595 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91