HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0010468 - regulation of gene expression
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 326
+	Hs
		128021 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		718085 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717853 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718375 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718105 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717783 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718076 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		516378 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		718399 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36
+	Hs
		1294230 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1031435 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1273055 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		282658 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		282659 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00
+	Hs
		282502 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00