HitPredict

Interactor 1: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19690564
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 353 Hs			1 318
+	Hs
		1155574 Q6NR77_HUMAN (1-324): 1.03e-80: 251: 99.69		UB2J1_HUMAN (1-318): 2.47e-117: 342: 100.00
+	Hs
		1151762 Q6GX22_HUMAN (14-337): 5.23e-87: 277: 23.68		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		919810 TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		849393 TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		895866 TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		584923 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		584907 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		584916 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		1281989 TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	Hs
		1317493 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		919848 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		849433 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		849434 TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		895851 TRI58_HUMAN (8-353): 5.49e-73: 235: 13.87		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		895900 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		895901 TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		584910 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	Hs
		908264 TRI63_HUMAN (1-326): 8.01e-81: 252: 100.00		UB2G1_HUMAN (15-148): 2.26e-56: 182: 25.83
+	Hs
		1282342 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	Hs
		584914 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		UB2G2_HUMAN (7-142): 5.84e-58: 185: 26.00