HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 1235
+	Hs
		1017308 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		1017333 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		1087312 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		707702 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		241661 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		TRI33_HUMAN (820-1232): 7.65e-33: 140: 11.56
+	Hs
		170383 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		170321 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		1087422 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		707758 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		998782 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		707606 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		1087228 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		707673 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		846990 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		846915 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		1087293 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		PHIP_HUMAN (1059-1206): 1.19e-14: 81.5: 15.23
+	Hs
		1087311 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		707701 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		1087308 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22
+	Hs
		707700 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22