HitPredict

Interactor 1: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Interactor 2: TCF20 (Q9UGU0)
Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein)
Gene: TCF20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Hs			1 1960
+	Hs
		1087462 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		TCF20_HUMAN (1-1960): 0: 925: 100.00
+	Hs
		707782 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		TCF20_HUMAN (1-1960): 0: 925: 100.00
+	Hs
		1087223 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Hs
		1191020 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Hs
		707670 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Hs
		918475 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		RAI1_HUMAN (1-1933): 2.26e-103: 371: 20.28
+	Hs
		1087483 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		KMT2B_HUMAN (1766-1932): 1.68e-35: 151: 19.05
+	Hs
		975269 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		241509 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		707596 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		918303 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		KMT2A_HUMAN (1765-1933): 1.16e-32: 142: 20.00
+	Hs
		707682 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		PHF6_HUMAN (1814-1946): 5.25e-24: 108: 21.38
+	Hs
		918501 H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04		PHF6_HUMAN (1814-1946): 5.25e-24: 108: 21.38
+	Hs
		1129830 H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54
+	Hs
		1087299 H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54
+	Hs
		617962 H2B1O_HUMAN (5-127): 3.41e-54: 167: 86.18		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54
+	Hs
		1264778 H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54
+	Hs
		241595 H2B1K_HUMAN (1-127): 8.56e-54: 166: 84.25		TITIN_HUMAN (744-1529): 2.73e-10: 68.4: 11.54
+	Hs
		152598 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		KMT2D_HUMAN (207-917): 2.24e-09: 65.3: 9.99
+	Hs
		707690 H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83		KMT2C_HUMAN (307-902): 2.88e-09: 64.9: 11.15