HitPredict

Interactor 1: UPP (Q96BW1)
Uracil phosphoribosyltransferase homolog
Gene: UPRT

Interactor 2: UCK1 (Q9HA47)
Uridine-cytidine kinase 1 (UCK 1) (EC 2.7.1.48) (Cytidine monophosphokinase 1) (Uridine monophosphokinase 1)
Gene: UCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0050262 - ribosylnicotinamide kinase activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 277
+	Hs
		1285957 UPP_HUMAN (1-309): 7.54e-156: 439: 100.00		UCK2_HUMAN (6-277): 1.98e-111: 323: 68.25
+	Hs
		1285960 UPP_HUMAN (1-309): 7.54e-156: 439: 100.00		UCKL1_HUMAN (15-275): 3.95e-104: 315: 40.51
+	Hs
		1318493 UCKL1_HUMAN (14-309): 8.66e-117: 348: 31.92		UCK2_HUMAN (6-277): 1.98e-111: 323: 68.25
+	Zm
		45677 A0A1D6QVF4_MAIZE (14-309): 1.56e-94: 291: 30.93		A0A1D6QVF4_MAIZE (7-275): 2.53e-111: 333: 43.96
+	Dm
		1228811 Q9VRQ1_DROME (101-309): 1.92e-98: 291: 66.03		Q8MQK4_DROME (22-275): 2.33e-101: 310: 42.32
+	Dm
		116072 M9PHI7_DROME (101-308): 5.64e-96: 285: 64.90		Q8MQK4_DROME (22-275): 2.33e-101: 310: 42.32
+	Ce
		1353641 Q9U3L5_CAEEL (103-307): 3.72e-86: 260: 50.73		Q9U3I7_CAEEL (15-275): 2.06e-103: 313: 42.14
+	Sp
		143434 UPP1_SCHPO (103-308): 9.71e-99: 291: 46.98		URK1_SCHPO (11-266): 2.81e-90: 276: 35.42
+	Sc
		577547 UPP_YEAST (102-306): 4.97e-99: 291: 46.73		URK1_YEAST (9-267): 6.7e-80: 251: 34.55
+	Ce
		1088909 Q9U3I7_CAEEL (11-308): 1.03e-98: 302: 28.57		UCK_CAEEL (20-233): 3.8e-78: 238: 48.17
+	Sc
		649009 URK1_YEAST (14-309): 2.7e-71: 230: 23.00		URK1_YEAST (9-267): 6.7e-80: 251: 34.55
+	Sc
		649026 URK1_YEAST (14-309): 2.7e-71: 230: 23.00		DAS2_YEAST (21-230): 6.45e-46: 155: 24.30