HitPredict

Interactor 1: DNM1L (O00429)
Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)
Gene: DNM1L

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	18330356
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008289 - lipid binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 368
+	Hs
		983404 DYN1_HUMAN (1-735): 0: 825: 38.64		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Mm
		760453 DYN1_MOUSE (1-735): 0: 827: 38.77		SH3G1_MOUSE (1-368): 7.42e-89: 273: 94.02
+	Hs
		128646 DNM1L_HUMAN (1-736): 0: 902: 100.00		SHLB2_HUMAN (10-363): 1.2e-58: 196: 22.39
+	Mm
		760455 DYN1_MOUSE (1-735): 0: 827: 38.77		SH3G3_MOUSE (1-367): 8.72e-87: 267: 63.76
+	Rn
		193636 DYN1_RAT (1-735): 0: 819: 38.90		SH3G1_RAT (1-368): 5.26e-88: 271: 92.94
+	Mm
		760454 DYN1_MOUSE (1-735): 0: 827: 38.77		SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02
+	Hs
		983405 DYN1_HUMAN (1-735): 0: 825: 38.64		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Rn
		192351 DYN1_RAT (1-735): 0: 819: 38.90		SH3G2_RAT (1-368): 2.02e-84: 261: 68.48
+	Rn
		192355 DYN1_RAT (1-735): 0: 819: 38.90		SH3G3_RAT (1-368): 2.22e-84: 261: 62.77
+	Mm
		760467 DYN1_MOUSE (1-735): 0: 827: 38.77		SHLB1_MOUSE (10-363): 3.6e-69: 223: 25.00
+	Hs
		983392 DYN1_HUMAN (1-735): 0: 825: 38.64		NOSTN_HUMAN (5-364): 1.09e-39: 149: 17.34
+	Hs
		983406 DYN1_HUMAN (1-735): 0: 825: 38.64		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Mm
		760451 DYN1_MOUSE (1-735): 0: 827: 38.77		PACN1_MOUSE (16-363): 2.86e-35: 135: 14.61
+	Hs
		983417 DYN1_HUMAN (1-735): 0: 825: 38.64		PACN2_HUMAN (16-364): 1.92e-34: 134: 14.97
+	Rn
		599414 DYN1_RAT (1-735): 0: 819: 38.90		PACN1_RAT (16-363): 7.8e-36: 137: 14.61
+	Mm
		760450 DYN1_MOUSE (1-735): 0: 827: 38.77		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924499 DYN1_HUMAN (1-735): 0: 825: 38.64		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Rn
		192739 DYN1_RAT (1-735): 0: 819: 38.90		SRBS2_RAT (264-363): 2.11e-12: 70.5: 22.55
+	Rn
		599402 DYN1_RAT (1-735): 0: 819: 38.90		GRB2_RAT (311-367): 1.59e-11: 65.2: 41.38
+	Mm
		1141147 DYN3_MOUSE (1-735): 0: 815: 38.09		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38