Protein: DSG4
Desmoglein-4 (Cadherin family member 13)

Gene: DSG4
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q86SJ6

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0001942 - hair follicle development
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1197787

JAM1
Junctional adhesion molecule A

1

12

High-throughput

0.691

High

171412

SMAD9
Mothers against decapentaplegic homolog 9

3

4

High-throughput

0.667

High

1197765

O51E2
Olfactory receptor 51E2

3

0

High-throughput

0.638

High

380122

MAS
Proto-oncogene Mas

2

4

High-throughput

0.628

High

1197743

IL31R
Interleukin-31 receptor subunit alpha

2

15

High-throughput

0.628

High

800906

MK09
Mitogen-activated protein kinase 9

2

5

High-throughput

0.611

High

1197741

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

3

2

High-throughput

0.609

High

1197751

TFG
Protein TFG

3

1

High-throughput

0.609

High

1197744

GRP4
RAS guanyl-releasing protein 4

2

0

High-throughput

0.602

High

1197763

REEP2
Receptor expression-enhancing protein 2

2

0

High-throughput

0.602

High

178974

FOXP2
Forkhead box protein P2

2

2

High-throughput

0.574

High

390988

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

3

High-throughput

0.574

High

1089400

SYT16
Synaptotagmin-16

2

1

High-throughput

0.574

High

1145404

LPCT4
Lysophospholipid acyltransferase LPCAT4

2

1

High-throughput

0.574

High

1197749

FAN
Protein FAN

2

2

High-throughput

0.574

High

1197755

RM38
Large ribosomal subunit protein mL38

2

1

High-throughput

0.574

High

1197779

FBXL4
F-box/LRR-repeat protein 4

2

3

High-throughput

0.574

High

1197781

OAZ3
Ornithine decarboxylase antizyme 3

2

1

High-throughput

0.574

High

1197785

KIF3A
Kinesin-like protein KIF3A

2

3

High-throughput

0.574

High

1079934

RB11B
Ras-related protein Rab-11B

2

9

High-throughput

0.558

High

1197736

ELMD1
ELMO domain-containing protein 1

2

1

High-throughput

0.558

High

281996

ANXA9
Annexin A9

1

7

High-throughput

0.536

High

341163

C1R
Complement C1r subcomponent

1

10

High-throughput

0.536

High

713831

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.536

High

723739

DRD3
D(3) dopamine receptor

1

1

High-throughput

0.536

High

925399

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.536

High

970712

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

8

High-throughput

0.536

High

1017588

FSTL1
Follistatin-related protein 1

1

2

High-throughput

0.536

High

1032197

ITAD
Integrin alpha-D

1

6

High-throughput

0.536

High

1054974

SPRL1
SPARC-like protein 1

1

2

High-throughput

0.536

High

1153648

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

2

High-throughput

0.536

High

1197752

US6NL
USP6 N-terminal-like protein

1

4

High-throughput

0.536

High

1197762

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

3

High-throughput

0.536

High

1197771

RAB9B
Ras-related protein Rab-9B

1

12

High-throughput

0.536

High

1197773

NPAP1
Nuclear pore-associated protein 1

1

6

High-throughput

0.536

High

714921

BTC
Probetacellulin [Cleaved into: Betacellulin

1

0

High-throughput

0.513

High

1197756

DTBP1
Dysbindin

1

0

High-throughput

0.513

High

1197770

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.513

High

1197784

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.513

High

49100

DHR12
Dehydrogenase/reductase SDR family member 12

1

5

High-throughput

0.489

High

127113

FOXN3
Forkhead box protein N3

1

2

High-throughput

0.489

High

304982

DUS14
Dual specificity protein phosphatase 14

1

3

High-throughput

0.489

High

345479

FOS
Protein c-Fos

1

2

High-throughput

0.489

High

714975

PROF2
Profilin-2

1

1

High-throughput

0.489

High

813089

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.489

High

851562

NEK4
Serine/threonine-protein kinase Nek4

1

12

High-throughput

0.489

High

1065042

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

1

High-throughput

0.489

High

1124728

YIF1B
Protein YIF1B

1

1

High-throughput

0.489

High

1197730

CACL1
CDK2-associated and cullin domain-containing protein 1

1

7

High-throughput

0.489

High

1197739

RDH13
Retinol dehydrogenase 13

1

5

High-throughput

0.489

High

1197742

BHE23
Class E basic helix-loop-helix protein 23

1

1

High-throughput

0.489

High

1197746

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

3

High-throughput

0.489

High

1197754

OTUL
Ubiquitin thioesterase otulin

1

2

High-throughput

0.489

High

1197759

ZN597
Zinc finger protein 597

1

1

High-throughput

0.489

High

1197766

SRMS
Tyrosine-protein kinase Srms

1

10

High-throughput

0.489

High

1197780

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.489

High

1197782

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

5

High-throughput

0.489

High

487989

RARA
Retinoic acid receptor alpha

1

8

Small-scale

0.479

High

1197729

P2RY8
P2Y purinoceptor 8

1

3

High-throughput

0.479

High

377441

GCR
Glucocorticoid receptor

1

9

High-throughput

0.437

High

618655

IF4B
Eukaryotic translation initiation factor 4B

1

2

Small-scale

0.437

High

1197750

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1197764

DDX24
ATP-dependent RNA helicase DDX24

1

5

High-throughput

0.437

High

891202

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

4

High-throughput

0.407

High

274689

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

3

0

High-throughput

0.347

High

1122394

SGO2
Shugoshin 2

3

0

High-throughput

0.347

High

1132395

TEX35
Testis-expressed protein 35

3

0

High-throughput

0.347

High

1153863

IFIX
Pyrin and HIN domain-containing protein 1

3

0

High-throughput

0.347

High

1197733

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.347

High

1197753

PMM1
Phosphomannomutase 1

3

0

High-throughput

0.347

High

1197757

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

3

0

High-throughput

0.347

High

1197758

MTNB
Methylthioribulose-1-phosphate dehydratase

3

0

High-throughput

0.347

High

1197776

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.347

High

882137

GSC
Homeobox protein goosecoid

2

0

High-throughput

0.328

High

1012579

CF210
Cilia- and flagella- associated protein 210

2

0

High-throughput

0.328

High

1197734

S22A9
Organic anion transporter 7

2

0

High-throughput

0.328

High

1197747

CPLX3
Complexin-3

2

0

High-throughput

0.328

High

1197761

SETB2
Histone-lysine N-methyltransferase SETDB2

2

0

High-throughput

0.328

High

1197768

ZMAT4
Zinc finger matrin-type protein 4

2

0

High-throughput

0.328

High

1023386

COASY
Bifunctional coenzyme A synthase

2

0

High-throughput

0.318

High

238042

UD19
UDP-glucuronosyltransferase 1A9

1

0

High-throughput

0.279

Low

267015

SRS10
Serine/arginine-rich splicing factor 10

1

0

High-throughput

0.279

Low

439140

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

708236

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

821588

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.279

Low

826465

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

1127361

CX066
Uncharacterized protein CXorf66

1

0

High-throughput

0.279

Low

1167504

HEPN1
Putative cancer susceptibility gene HEPN1 protein

1

0

High-throughput

0.279

Low

1186171

DYM
Dymeclin

1

0

High-throughput

0.279

Low

1197728

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1197731

DOPP1
Dolichyldiphosphatase 1

1

0

High-throughput

0.279

Low

1197732

TF2LX
Homeobox protein TGIF2LX

1

0

High-throughput

0.279

Low

1197735

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1197737

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

1197738

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.279

Low

1197740

TM35B
Transmembrane protein 35B

1

0

High-throughput

0.279

Low

1197745

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

0

High-throughput

0.279

Low

1197748

SKA2
Spindle and kinetochore-associated protein 2

1

0

High-throughput

0.279

Low

1197760

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

1197767

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.279

Low

1197769

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.279

Low

1197774

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

1197775

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low

1197777

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.279

Low

1197778

FBX3
F-box only protein 3

1

0

High-throughput

0.279

Low

1197783

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

1197786

MTL5
Tesmin

1

0

High-throughput

0.279

Low

1197772

SPNXC
Sperm protein associated with the nucleus on the X chromosome C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024