HitPredict

Interactor 1: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	33545068, 34964704
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 125
+	Hs
		1287491 AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Mm
		950912 AP2M1_MOUSE (1-435): 1.03e-178: 507: 100.00		MLP3A_MOUSE (1-120): 8.21e-55: 168: 82.50
+	Sc
		745036 AP3M_YEAST (53-434): 2.96e-57: 197: 17.77		ATG8_YEAST (4-120): 5.69e-55: 168: 34.19