HitPredict

Interactor 1: Q96D37 (Q96D37)
VAV1 protein (Vav guanine nucleotide exchange factor 1)
Gene: VAV1

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2213
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 790 Hs			1 817
+	Hs
		548744 VAV_HUMAN (12-790): 0: 613: 99.74		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Hs
		1301988 ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Mm
		1141818 ARHG2_MOUSE (28-458): 1.23e-72: 258: 15.04		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		1333801 ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49		NEB1_HUMAN (1-817): 2.29e-110: 364: 46.47
+	Mm
		1141820 ARHG2_MOUSE (28-458): 1.23e-72: 258: 15.04		Q7TN74_MOUSE (1-817): 5.32e-108: 358: 45.12
+	Mm
		57860 KALRN_MOUSE (85-612): 4.74e-65: 238: 15.91		Q7TN74_MOUSE (1-817): 5.32e-108: 358: 45.12
+	Hs
		1066045 ARHG6_HUMAN (677-788): 1.53e-14: 79.8: 23.21		NEB2_HUMAN (1-817): 3.09e-122: 389: 100.00
+	Ce
		136804 VAV_CAEEL (14-787): 2.18e-102: 340: 21.71		UNC89_CAEEL (2-312): 5.97e-20: 98.3: 14.29
+	Hs
		1301448 ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Hs
		224720 KALRN_HUMAN (85-612): 8.98e-65: 238: 16.67		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Mm
		57820 KALRN_MOUSE (85-612): 4.74e-65: 238: 15.91		H3BJA6_MOUSE (342-543): 3.63e-47: 169: 49.57
+	Hs
		224721 KALRN_HUMAN (85-612): 8.98e-65: 238: 16.67		LNX1_HUMAN (273-773): 3.79e-34: 142: 13.78
+	Mm
		57873 KALRN_MOUSE (85-612): 4.74e-65: 238: 15.91		DLG2_MOUSE (419-621): 1.35e-28: 125: 21.18
+	Mm
		57852 KALRN_MOUSE (85-612): 4.74e-65: 238: 15.91		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Hs
		1050065 ECT2_HUMAN (28-572): 6.7e-72: 255: 16.49		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Dm
		55850 A1ZBA1_DROME (131-445): 4.11e-15: 82: 23.99		M9NFI9_DROME (255-816): 1.29e-53: 204: 33.63
+	Hs
		1049726 ARHG7_HUMAN (686-788): 2.09e-15: 82.5: 23.30		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Dm
		993190 GRAP_DROME (562-787): 4.18e-19: 88.6: 28.63		Q8IPP3_DROME (479-613): 8.37e-40: 161: 34.07
+	Hs
		1049703 ARHG7_HUMAN (686-788): 2.09e-15: 82.5: 23.30		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15
+	Hs
		1049952 ARHG6_HUMAN (677-788): 1.53e-14: 79.8: 23.21		SCRIB_HUMAN (412-596): 5.32e-14: 78.7: 21.15