HitPredict

Interactor 1: REPS1 (Q96D71)
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)
Gene: REPS1

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005905 - clathrin-coated pit and 1 others more... GO:0006897 - endocytosis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1294
+	Hs
		1349284 ITSN2_HUMAN (4-793): 2.76e-89: 310: 12.97		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1244791 REPS2_HUMAN (4-796): 3.9e-87: 291: 32.23		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1353928 EP15R_HUMAN (8-735): 2e-72: 256: 13.93		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1357258 SYNRG_HUMAN (15-788): 4.39e-54: 205: 10.71		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1078932 ITSN1_HUMAN (1-115): 1.23e-17: 90.4: 16.52		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		787993 EPS15_HUMAN (4-782): 1.98e-17: 89.3: 10.12		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		724698 EPS15_HUMAN (4-782): 1.98e-17: 89.3: 10.12		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70