Protein: CDC16
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)

Gene: CDC16
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q13042

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672822

CDC27
Cell division cycle protein 27 homolog

25

17

Small-scale

0.990

High

1022947

CDC26
Anaphase-promoting complex subunit CDC26

13

6

Small-scale

0.986

High

1023015

CDC23
Cell division cycle protein 23 homolog

7

17

High-throughput

0.967

High

1023016

APC7
Anaphase-promoting complex subunit 7

6

17

High-throughput

0.950

High

1022965

APC16
Anaphase-promoting complex subunit 16

5

5

High-throughput

0.932

High

887545

APC15
Anaphase-promoting complex subunit 15

3

6

Small-scale

0.861

High

1022949

TTC8
Tetratricopeptide repeat protein 8

2

20

High-throughput

0.811

High

1023018

APC4
Anaphase-promoting complex subunit 4

15

11

Small-scale

0.762

High

1017371

CDC20
Cell division cycle protein 20 homolog

13

20

Small-scale

0.759

High

1023019

ANC2
Anaphase-promoting complex subunit 2

8

20

Small-scale

0.750

High

1023023

FZR1
Fizzy-related protein homolog

8

20

Small-scale

0.750

High

236919

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

7

18

Small-scale

0.744

High

1022981

APC1
Anaphase-promoting complex subunit 1

6

11

Small-scale

0.737

High

1023021

FBX5
F-box only protein 5

5

7

Small-scale

0.723

High

1023017

APC5
Anaphase-promoting complex subunit 5

5

12

High-throughput

0.720

High

851318

NEK2
Serine/threonine-protein kinase Nek2

5

12

Small-scale

0.712

High

1022975

APC13
Anaphase-promoting complex subunit 13

4

5

High-throughput

0.697

High

1023026

TRI33
E3 ubiquitin-protein ligase TRIM33

4

16

Small-scale

0.694

High

47925

IFT56
Intraflagellar transport protein 56

1

1

High-throughput

0.691

High

1023024

APC10
Anaphase-promoting complex subunit 10

4

18

Small-scale

0.691

High

294776

RECQ4
ATP-dependent DNA helicase Q4

3

9

High-throughput

0.667

High

327738

TTLL1
Polyglutamylase complex subunit TTLL1

3

2

High-throughput

0.667

High

1022894

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

3

8

Small-scale

0.650

High

1022899

MDC1
Mediator of DNA damage checkpoint protein 1

3

17

Small-scale

0.640

High

70672

MYO9A
Unconventional myosin-IXa

2

1

High-throughput

0.628

High

128846

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

2

2

High-throughput

0.628

High

170351

TIF1A
Transcription intermediary factor 1-alpha

2

16

High-throughput

0.628

High

211010

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

2

16

High-throughput

0.628

High

261491

NCOR1
Nuclear receptor corepressor 1

2

8

High-throughput

0.628

High

301794

TRI37
E3 ubiquitin-protein ligase TRIM37

2

13

High-throughput

0.628

High

840371

ERF
ETS domain-containing transcription factor ERF

2

1

High-throughput

0.628

High

1022907

TBB8
Tubulin beta-8 chain

2

8

High-throughput

0.628

High

1022908

ANO6
Anoctamin-6

2

3

High-throughput

0.628

High

1022912

CE350
Centrosome-associated protein 350

2

3

High-throughput

0.628

High

1022920

BCOR
BCL-6 corepressor

2

7

High-throughput

0.628

High

1022921

CO039
Uncharacterized protein C15orf39

2

8

High-throughput

0.628

High

1022922

FA83H
Protein FAM83H

2

1

High-throughput

0.628

High

1022927

TEDC1
Tubulin epsilon and delta complex protein 1

2

1

High-throughput

0.628

High

1022929

IQGA3
Ras GTPase-activating-like protein IQGAP3

2

2

High-throughput

0.628

High

1022930

HOOK3
Protein Hook homolog 3

2

1

High-throughput

0.628

High

1022931

LONP2
Lon protease homolog 2, peroxisomal

2

3

High-throughput

0.628

High

1022932

CEP97
Centrosomal protein of 97 kDa

2

2

High-throughput

0.628

High

1022934

MGAP
MAX gene-associated protein

2

2

High-throughput

0.628

High

1022937

RAVR1
Ribonucleoprotein PTB-binding 1

2

10

High-throughput

0.628

High

1022940

ASPM
Abnormal spindle-like microcephaly-associated protein

2

2

High-throughput

0.628

High

1022942

KIF2B
Kinesin-like protein KIF2B

2

6

High-throughput

0.628

High

1022950

ALMS1
Centrosome-associated protein ALMS1

2

11

High-throughput

0.628

High

1022961

MED12
Mediator of RNA polymerase II transcription subunit 12

2

6

High-throughput

0.628

High

1022976

HAUS8
HAUS augmin-like complex subunit 8

2

1

High-throughput

0.628

High

1022988

DHX35
Probable ATP-dependent RNA helicase DHX35

2

3

High-throughput

0.628

High

1022992

CSR2B
Cysteine-rich protein 2-binding protein

2

2

High-throughput

0.628

High

1022995

JMJD4
2-oxoglutarate and iron-dependent oxygenase JMJD4

2

6

High-throughput

0.628

High

1023001

DISC1
Disrupted in schizophrenia 1 protein

2

4

High-throughput

0.628

High

1023013

TRPS1
Zinc finger transcription factor Trps1

2

5

High-throughput

0.628

High

1023014

HOOK1
Protein Hook homolog 1

2

2

High-throughput

0.628

High

1023028

CE164
Centrosomal protein of 164 kDa

2

5

High-throughput

0.628

High

1023030

ZN281
Zinc finger protein 281

2

2

High-throughput

0.628

High

1022936

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

2

High-throughput

0.611

High

1022990

MAGIX
PDZ domain-containing protein MAGIX

3

6

High-throughput

0.609

High

800877

MK09
Mitogen-activated protein kinase 9

2

3

High-throughput

0.606

High

200554

CP110
Centriolar coiled-coil protein of 110 kDa

2

0

High-throughput

0.602

High

300895

HAUS5
HAUS augmin-like complex subunit 5

2

0

High-throughput

0.602

High

885513

MLF1
Myeloid leukemia factor 1

2

0

High-throughput

0.602

High

1017040

TROAP
Tastin

2

0

High-throughput

0.602

High

1022898

ESPL1
Separin

2

0

High-throughput

0.602

High

1022901

IQCB1
IQ calmodulin-binding motif-containing protein 1

2

0

High-throughput

0.602

High

1022902

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.602

High

1022910

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

2

0

High-throughput

0.602

High

1022913

ZN318
Zinc finger protein 318

2

0

High-throughput

0.602

High

1022915

HAUS3
HAUS augmin-like complex subunit 3

2

0

High-throughput

0.602

High

1022918

RICTR
Rapamycin-insensitive companion of mTOR

2

0

High-throughput

0.602

High

1022926

HAUS6
HAUS augmin-like complex subunit 6

2

0

High-throughput

0.602

High

1022941

ZN687
Zinc finger protein 687

2

0

High-throughput

0.602

High

1022944

SMG8
Nonsense-mediated mRNA decay factor SMG8

2

0

High-throughput

0.602

High

1022955

SMG7
Nonsense-mediated mRNA decay factor SMG7

2

0

High-throughput

0.602

High

1022974

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.602

High

1022977

TALD3
Protein TALPID3

2

0

High-throughput

0.602

High

1022978

CE295
Centrosomal protein of 295 kDa

2

0

High-throughput

0.602

High

1022991

YYAP1
YY1-associated protein 1

2

0

High-throughput

0.602

High

1022999

MYO5C
Unconventional myosin-Vc

2

0

High-throughput

0.602

High

1023000

4ET
Eukaryotic translation initiation factor 4E transporter

2

0

High-throughput

0.602

High

1023004

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.602

High

1023006

GTSE1
G2 and S phase-expressed protein 1

2

0

High-throughput

0.602

High

1023020

TASOR
Protein TASOR

2

0

High-throughput

0.602

High

917193

H4
Histone H4

2

6

High-throughput

0.584

High

998630

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.584

High

1023012

ZRAN1
Ubiquitin thioesterase ZRANB1

2

7

High-throughput

0.584

High

1022909

Q4KMX6
ANAPC7 protein

1

17

High-throughput

0.575

High

166166

ZBTB5
Zinc finger and BTB domain-containing protein 5

2

3

High-throughput

0.574

High

1022914

RSBN1
Lysine-specific demethylase 9

2

1

High-throughput

0.574

High

1022916

PHLB3
Pleckstrin homology-like domain family B member 3

2

1

High-throughput

0.574

High

1022917

CP087
UPF0547 protein C16orf87

2

4

High-throughput

0.574

High

1022919

SAMD1
Sterile alpha motif domain-containing protein 1

2

2

High-throughput

0.574

High

1022925

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

2

High-throughput

0.574

High

1022946

GP156
Probable G-protein coupled receptor 156

2

1

High-throughput

0.574

High

1022964

P5CR2
Pyrroline-5-carboxylate reductase 2

2

4

High-throughput

0.574

High

1022966

DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

2

1

High-throughput

0.574

High

1022971

SNX18
Sorting nexin-18

2

3

High-throughput

0.574

High

1022986

ZN644
Zinc finger protein 644

2

1

High-throughput

0.574

High

1023031

SALL2
Sal-like protein 2

2

1

High-throughput

0.574

High

369508

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

1022957

ESR2
Estrogen receptor beta

2

18

High-throughput

0.571

High

1023005

APC11
Anaphase-promoting complex subunit 11

2

10

High-throughput

0.552

High

237209

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.536

High

318956

CEP43
Centrosomal protein 43

1

1

High-throughput

0.536

High

426630

H10
Histone H1.0

1

2

High-throughput

0.536

High

508491

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

679612

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

2

High-throughput

0.536

High

828753

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

868462

ATX1
Ataxin-1

1

2

High-throughput

0.536

High

928891

SKP1
S-phase kinase-associated protein 1

1

2

High-throughput

0.536

High

1022900

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

1022905

H2B2E
Histone H2B type 2-E

1

6

High-throughput

0.536

High

1022906

FHOD3
FH1/FH2 domain-containing protein 3

1

6

High-throughput

0.536

High

1022933

MA7D3
MAP7 domain-containing protein 3

1

6

High-throughput

0.536

High

1022948

KI18A
Kinesin-like protein KIF18A

1

7

High-throughput

0.536

High

1022953

PSPC1
Paraspeckle component 1

1

10

High-throughput

0.536

High

1022958

THRSP
Thyroid hormone-inducible hepatic protein

1

1

High-throughput

0.536

High

1022962

SPSB4
SPRY domain-containing SOCS box protein 4

1

10

High-throughput

0.536

High

1022968

NSUN5
28S rRNA

1

2

High-throughput

0.536

High

1022973

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

1022983

FA83D
Protein FAM83D

1

1

High-throughput

0.536

High

1022987

RABE2
Rab GTPase-binding effector protein 2

1

4

High-throughput

0.536

High

1023009

E2AK4
eIF-2-alpha kinase GCN2

1

8

High-throughput

0.536

High

1023022

YETS2
YEATS domain-containing protein 2

1

3

High-throughput

0.536

High

1022989

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.518

High

1022893

TADBP
TAR DNA-binding protein 43

1

9

High-throughput

0.515

High

206359

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.513

High

456320

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

1

0

High-throughput

0.513

High

1022938

TRM44
Probable tRNA

1

0

High-throughput

0.513

High

1022951

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.513

High

1022954

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.513

High

1022972

GCP6
Gamma-tubulin complex component 6

1

0

High-throughput

0.513

High

1022980

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.513

High

1022993

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.513

High

1023025

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.513

High

1022904

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

7

Small-scale

0.501

High

687204

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

4

High-throughput

0.489

High

1022952

DEP1B
DEP domain-containing protein 1B

1

2

High-throughput

0.489

High

1022994

ZN408
Zinc finger protein 408

1

3

High-throughput

0.489

High

1022997

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

5

High-throughput

0.489

High

1023008

CFA97
Cilia- and flagella-associated protein 97

1

3

High-throughput

0.489

High

1023011

B4GT7
Beta-1,4-galactosyltransferase 7

1

2

High-throughput

0.489

High

1023029

LTOR2
Ragulator complex protein LAMTOR2

1

2

High-throughput

0.489

High

524901

XRCC5
X-ray repair cross-complementing protein 5

1

1

High-throughput

0.481

High

681418

DNJA1
DnaJ homolog subfamily A member 1

1

5

High-throughput

0.481

High

957173

DAB2
Disabled homolog 2

1

1

High-throughput

0.481

High

122717

MEN1
Menin

1

2

High-throughput

0.479

High

160541

AURKA
Aurora kinase A

1

6

High-throughput

0.479

High

208260

DCX
Neuronal migration protein doublecortin

1

2

Small-scale

0.479

High

227316

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.479

High

237592

DIAP1
Protein diaphanous homolog 1

1

6

High-throughput

0.479

High

244366

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

322549

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

374149

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

414264

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.479

High

538535

CCNB1
G2/mitotic-specific cyclin-B1

1

11

Small-scale

0.479

High

552608

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

656213

PSA5
Proteasome subunit alpha type-5

1

5

Small-scale

0.479

High

668639

PML
Protein PML

1

13

High-throughput

0.479

High

673271

WEE1
Wee1-like protein kinase

1

11

High-throughput

0.479

High

708288

TTK
Dual specificity protein kinase TTK

1

10

Small-scale

0.479

High

739702

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.479

High

749436

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

779327

CCNF
Cyclin-F

1

15

High-throughput

0.479

High

823380

PAXI
Paxillin

1

3

High-throughput

0.479

High

861727

PLK1
Serine/threonine-protein kinase PLK1

1

10

High-throughput

0.479

High

897236

CSN2
COP9 signalosome complex subunit 2

1

6

Small-scale

0.479

High

910398

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

930824

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

7

Small-scale

0.479

High

934713

H31
Histone H3.1

1

7

High-throughput

0.479

High

950162

SMAD3
Mothers against decapentaplegic homolog 3

1

6

Small-scale

0.479

High

961082

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

1018938

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

1022896

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1022903

SMAD2
Mothers against decapentaplegic homolog 2

1

6

Small-scale

0.479

High

1022923

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.479

High

1022924

PAXI1
PAX-interacting protein 1

1

9

High-throughput

0.479

High

1022928

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

7

Small-scale

0.479

High

1022935

CUL9
Cullin-9

1

6

Small-scale

0.479

High

1022943

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1022945

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

12

Small-scale

0.479

High

1022956

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1022959

REQU
Zinc finger protein ubi-d4

1

13

High-throughput

0.479

High

1022960

CBP
CREB-binding protein

1

17

Small-scale

0.479

High

1022963

SH3K1
SH3 domain-containing kinase-binding protein 1

1

11

High-throughput

0.479

High

1022969

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

1022970

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

3

Small-scale

0.479

High

1022979

WWTR1
WW domain-containing transcription regulator protein 1

1

8

High-throughput

0.479

High

1022982

P63
Tumor protein 63

1

4

Small-scale

0.479

High

1022984

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

10

High-throughput

0.479

High

1022985

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1022996

PKHA5
Pleckstrin homology domain-containing family A member 5

1

12

Small-scale

0.479

High

1022998

ANLN
Anillin

1

1

High-throughput

0.479

High

1023002

LATS2
Serine/threonine-protein kinase LATS2

1

3

Small-scale

0.479

High

1023007

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

1023010

HECW2
E3 ubiquitin-protein ligase HECW2

1

8

High-throughput

0.479

High

1023027

PHF8
Histone lysine demethylase PHF8

1

6

Small-scale

0.479

High

365189

FRIH
Ferritin heavy chain

1

0

High-throughput

0.460

High

834482

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.460

High

964315

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1023032

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

0

High-throughput

0.458

High

92420

E9PDP5
Ankyrin repeat and KH domain containing 1

1

2

High-throughput

0.445

High

211167

BUB3
Mitotic checkpoint protein BUB3

1

10

High-throughput

0.445

High

1022895

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.445

High

1022897

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

1022967

CEP63
Centrosomal protein of 63 kDa

1

2

High-throughput

0.445

High

319181

BRD1
Bromodomain-containing protein 1

1

6

High-throughput

0.437

High

391678

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.437

High

61123

KRBA1
Protein KRBA1

2

0

High-throughput

0.328

High

66887

YDJC
Carbohydrate deacetylase

2

0

High-throughput

0.328

High

1022939

IZUM1
Izumo sperm-egg fusion protein 1

2

0

High-throughput

0.328

High

473059

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

579532

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.279

Low

1022911

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1023003

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.279

Low

825690

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

66877

D11L8
Putative ATP-dependent RNA helicase DDX11-like protein 8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024