HitPredict

Interactor 1: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Interactor 2: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 357 Hs			1 1166
+	Hs
		1146832 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		TNKS2_HUMAN (28-1166): 0: 891: 98.60
+	Hs
		1146620 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		ANR44_HUMAN (526-1140): 1.67e-83: 295: 16.87
+	Mm
		71296 A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56		ANR44_MOUSE (525-1140): 5.01e-83: 294: 17.43
+	Hs
		166894 LIS1_HUMAN (278-355): 3.21e-19: 90.1: 20.51		ANR28_HUMAN (7-525): 2.62e-78: 281: 22.10
+	Hs
		903354 WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72
+	Hs
		1146951 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		ANR50_HUMAN (693-1154): 6.7e-43: 173: 12.72
+	Hs
		1021417 A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87		ANK3_HUMAN (836-1140): 9.74e-22: 104: 9.18
+	Hs
		1219809 FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17		ANKH1_HUMAN (2-117): 5.71e-23: 108: 26.72