Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24613305
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005813 - centrosome
and 5 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 970
Hs

1 603
+ Hs
+ Mm
+ At
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+ Zm
+ At
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+ At
+ Sc
+ At
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+ At
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+ Hs
+ Sc

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Last updated: 15 Jul 2024