Interactor 1: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31
Interactor 2: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.771 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26670046, 26525107, 22791023, 28514442, 28978479, 27307491, 27545878, 29997244, 29892012, 26264872, 32019898, 33329596, 33215740, 33961781, 34755089, 35869046, 36276481, 36640323, 20005846, 22430200 and 14 others
more... |
| Identification Methods | affinity chromatography technology, pull down, biochemical, fluorescent resonance energy transfer, two hybrid, enzymatic study, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping and 6 others
more... |
| Interaction Type | physical association, direct interaction, association, ubiquitination reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol GO:0042742 - defense response to bacterium GO:0043123 - positive regulation of canonical NF-kappaB signal transduction and 6 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
