Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4

Interactor 2: STIL (Q15468)
SCL-interrupting locus protein (TAL-1-interrupting locus protein)
Gene: STIL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.55 0.649

The method score is based on:

Property Details
Experiments 24613305, 27872092, 26188084
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, pull down, protein kinase assay, isothermal titration calorimetry
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization
GO:0046601 - positive regulation of centriole replication
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024