Protein: QKI
KH domain-containing RNA-binding protein QKI (Protein quaking) (Hqk) (HqkI)

Gene: QKI
Organism: Homo sapiens
Interactions: 190
UniProt ID: Q96PU8

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

965834

HNRPK
Heterogeneous nuclear ribonucleoprotein K

7

19

High-throughput

0.974

High

1393927

FUBP3
Far upstream element-binding protein 3

4

20

High-throughput

0.904

High

1146973

PCBP2
Poly(rC)-binding protein 2

2

18

High-throughput

0.791

High

1400089

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

2

19

Small-scale

0.776

High

211396

RFOX2
RNA binding protein fox-1 homolog 2

7

19

High-throughput

0.751

High

1146778

PCBP1
Poly(rC)-binding protein 1

1

15

High-throughput

0.740

High

1372041

RBPMS
RNA-binding protein with multiple splicing

6

3

High-throughput

0.738

High

1358650

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

4

13

High-throughput

0.706

High

687484

PTBP1
Polypyrimidine tract-binding protein 1

3

14

High-throughput

0.678

High

794591

RBMX
RNA-binding motif protein, X chromosome

3

19

High-throughput

0.667

High

944897

PCBP4
Poly(rC)-binding protein 4

1

19

High-throughput

0.656

High

1400057

QKI
KH domain-containing RNA-binding protein QKI

1

15

High-throughput

0.656

High

537743

HSP7C
Heat shock cognate 71 kDa protein

3

4

High-throughput

0.650

High

478167

SNRPA
U1 small nuclear ribonucleoprotein A

2

17

High-throughput

0.633

High

250779

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

2

9

High-throughput

0.628

High

1066002

VAC14
Protein VAC14 homolog

2

5

High-throughput

0.628

High

1390281

TRI11
E3 ubiquitin-protein ligase TRIM11

2

2

High-throughput

0.628

High

1400097

FBW1B
F-box/WD repeat-containing protein 11

2

7

High-throughput

0.628

High

944847

PCBP3
Poly(rC)-binding protein 3

1

15

High-throughput

0.621

High

1400096

PTBP2
Polypyrimidine tract-binding protein 2

2

11

High-throughput

0.620

High

1400063

RBM42
RNA-binding protein 42

2

17

High-throughput

0.614

High

1029028

TIAR
Nucleolysin TIAR

2

6

High-throughput

0.606

High

332334

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.602

High

1358183

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

1311382

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

0

High-throughput

0.589

High

217184

MS18B
Protein Mis18-beta

2

0

High-throughput

0.585

High

401326

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

9

Small-scale

0.584

High

1397905

DMRTB
Doublesex- and mab-3-related transcription factor B1

2

2

High-throughput

0.584

High

225667

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

1400087

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

0

High-throughput

0.576

High

135319

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

20

High-throughput

0.575

High

1293401

CARM1
Histone-arginine methyltransferase CARM1

1

7

High-throughput

0.573

High

1400081

RFOX1
RNA binding protein fox-1 homolog 1

1

20

High-throughput

0.573

High

943300

RBM11
Splicing regulator RBM11

1

19

High-throughput

0.573

High

1383211

SOSB2
SOSS complex subunit B2

1

1

High-throughput

0.573

High

571686

HCLS1
Hematopoietic lineage cell-specific protein

1

7

High-throughput

0.541

High

927502

ATX1
Ataxin-1

1

1

High-throughput

0.541

High

1357978

RN138
E3 ubiquitin-protein ligase RNF138

1

9

High-throughput

0.541

High

1363751

PSMF1
Proteasome inhibitor PI31 subunit

1

2

High-throughput

0.541

High

1399693

RBM14
RNA-binding protein 14

1

11

High-throughput

0.541

High

1400107

USH1C
Harmonin

1

7

High-throughput

0.541

High

74576

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

17

High-throughput

0.536

High

256671

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

17

High-throughput

0.536

High

347262

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

389482

FINC
Fibronectin

1

3

High-throughput

0.536

High

462579

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

17

High-throughput

0.536

High

576510

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

13

High-throughput

0.536

High

931069

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1009291

PRR3
Proline-rich protein 3

1

2

High-throughput

0.536

High

1090280

ELAV2
ELAV-like protein 2

1

13

High-throughput

0.536

High

1148764

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

12

High-throughput

0.536

High

1168866

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

4

High-throughput

0.536

High

1307509

RBM45
RNA-binding protein 45

1

13

High-throughput

0.536

High

1370991

TNPO1
Transportin-1

1

3

High-throughput

0.536

High

887139

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.527

High

897552

BPL1
Biotin--protein ligase

1

0

High-throughput

0.518

High

1016367

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.518

High

1400080

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.518

High

1386541

OPTN
Optineurin

1

7

High-throughput

0.515

High

652392

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.513

High

1257986

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.513

High

1400061

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

1400077

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

685691

U2AF2
Splicing factor U2AF 65 kDa subunit

1

15

High-throughput

0.508

High

938780

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

8

High-throughput

0.508

High

1287687

RBM23
Probable RNA-binding protein 23

1

11

High-throughput

0.508

High

1400062

MEP50
Methylosome protein WDR77

1

7

High-throughput

0.508

High

1400098

RALY
RNA-binding protein Raly

1

7

High-throughput

0.508

High

1400104

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

209094

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.489

High

297671

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.481

High

298058

SPF27
Pre-mRNA-splicing factor SPF27

1

1

High-throughput

0.481

High

321637

PRP6
Pre-mRNA-processing factor 6

1

6

High-throughput

0.481

High

336753

BAG4
BAG family molecular chaperone regulator 4

1

2

High-throughput

0.481

High

480274

RU1C
U1 small nuclear ribonucleoprotein C

1

4

High-throughput

0.481

High

718902

CCND3
G1/S-specific cyclin-D3

1

1

High-throughput

0.481

High

937496

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

1

High-throughput

0.481

High

974271

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

5

High-throughput

0.481

High

1013967

TXN4A
Thioredoxin-like protein 4A

1

1

High-throughput

0.481

High

1052088

CALD1
Caldesmon

1

9

High-throughput

0.481

High

1206524

PRC2B
Protein PRRC2B

1

5

High-throughput

0.481

High

1219671

MBNL2
Muscleblind-like protein 2

1

2

High-throughput

0.481

High

1280722

YTHD3
YTH domain-containing family protein 3

1

7

High-throughput

0.481

High

1286256

PCGF5
Polycomb group RING finger protein 5

1

5

High-throughput

0.481

High

1329084

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

6

High-throughput

0.481

High

1336826

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

4

High-throughput

0.481

High

1387461

MSI2H
RNA-binding protein Musashi homolog 2

1

18

High-throughput

0.481

High

1400065

YTHD1
YTH domain-containing family protein 1

1

7

High-throughput

0.481

High

1400067

RM44
Large ribosomal subunit protein mL44

1

3

High-throughput

0.481

High

1400068

UNKL
Putative E3 ubiquitin-protein ligase UNKL

1

7

High-throughput

0.481

High

1400072

DAZ1
Deleted in azoospermia protein 1

1

10

Small-scale

0.481

High

1400073

MBNL1
Muscleblind-like protein 1

1

2

High-throughput

0.481

High

1400082

TSAP1
tRNA selenocysteine 1-associated protein 1

1

9

High-throughput

0.481

High

1400091

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.481

High

1400105

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

4

High-throughput

0.481

High

1400106

RBM7
RNA-binding protein 7

1

14

High-throughput

0.481

High

422938

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

48059

RBM47
RNA-binding protein 47

1

11

High-throughput

0.479

High

129345

MEN1
Menin

1

2

High-throughput

0.479

High

143201

NFIB
Nuclear factor 1 B-type

1

5

High-throughput

0.479

High

239607

MED14
Mediator of RNA polymerase II transcription subunit 14

1

4

High-throughput

0.479

High

260326

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

319990

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

326772

DUS14
Dual specificity protein phosphatase 14

1

3

High-throughput

0.479

High

336022

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.479

High

341651

EYA4
Protein phosphatase EYA4

1

9

High-throughput

0.479

High

372889

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

406530

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

472995

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.479

High

485349

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

18

High-throughput

0.479

High

607014

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

662639

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

2

High-throughput

0.479

High

713840

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

13

High-throughput

0.479

High

872649

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

980168

H4
Histone H4

1

2

High-throughput

0.479

High

1033163

EWS
RNA-binding protein EWS

1

10

High-throughput

0.479

High

1048067

TLE3
Transducin-like enhancer protein 3

1

5

High-throughput

0.479

High

1095047

DUS4
Dual specificity protein phosphatase 4

1

3

High-throughput

0.479

High

1151281

MED1
Mediator of RNA polymerase II transcription subunit 1

1

2

High-throughput

0.479

High

1152601

ELAV1
ELAV-like protein 1

1

8

High-throughput

0.479

High

1351130

SP7
Transcription factor Sp7

1

3

High-throughput

0.479

High

1352698

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1367060

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1369823

CELF1
CUGBP Elav-like family member 1

1

11

High-throughput

0.479

High

1372180

MED12
Mediator of RNA polymerase II transcription subunit 12

1

4

High-throughput

0.479

High

1387503

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

7

High-throughput

0.479

High

1393608

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1400058

MED15
Mediator of RNA polymerase II transcription subunit 15

1

5

High-throughput

0.479

High

1400075

RNC
Ribonuclease 3

1

4

High-throughput

0.479

High

1400076

DUS22
Dual specificity protein phosphatase 22

1

3

High-throughput

0.479

High

1400085

AATF
Protein AATF

1

1

High-throughput

0.479

High

1400093

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

1

Small-scale

0.479

High

1400094

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1400100

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

749111

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.460

High

1116567

FHL3
Four and a half LIM domains protein 3

1

0

High-throughput

0.460

High

1395801

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.460

High

1400059

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.460

High

1400060

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.460

High

1400074

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

1400090

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.460

High

1400101

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.460

High

282410

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.458

High

416038

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.458

High

667416

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

1241403

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

1259269

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.458

High

1400064

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.458

High

1400071

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1400079

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

1400083

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

1400084

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.458

High

1400095

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

1400099

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1400102

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.458

High

1400103

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.458

High

530242

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

942831

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.445

High

1016572

SRSF3
Serine/arginine-rich splicing factor 3

1

12

High-throughput

0.445

High

1227296

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.445

High

1253160

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.445

High

1400066

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

2

High-throughput

0.445

High

1400069

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.445

High

269465

KI21B
Kinesin-like protein KIF21B

1

1

High-throughput

0.439

High

1288040

PRP39
Pre-mRNA-processing factor 39

1

8

High-throughput

0.439

High

1400070

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

4

High-throughput

0.439

High

1400086

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

4

High-throughput

0.439

High

412459

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

938494

PAX9
Paired box protein Pax-9

1

1

High-throughput

0.437

High

1229042

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.437

High

1241330

CH082
UPF0598 protein C8orf82

1

2

High-throughput

0.437

High

1255133

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

353890

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.426

High

1104927

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.426

High

1400088

GLTP
Glycolipid transfer protein

1

0

High-throughput

0.426

High

619895

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.407

High

1333869

MFSD9
Major facilitator superfamily domain-containing protein 9

1

1

High-throughput

0.407

High

1197866

S39AC
Zinc transporter ZIP12

2

0

High-throughput

0.328

High

1400078

DEPP1
Protein DEPP1

1

0

High-throughput

0.282

High

561008

IL7
Interleukin-7

1

0

High-throughput

0.279

Low

1314988

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.251

Low

1336391

SLAI1
SLAIN motif-containing protein 1

1

0

High-throughput

0.251

Low

1400092

ZMAT5
Zinc finger matrin-type protein 5

1

0

High-throughput

0.251

Low

106497

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

294204

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1136674

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

1192281

ZACN
Ligand-gated cation channel ZACN

1

0

High-throughput

0.249

Low

1249132

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1357523

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025