Interactor 1: CHFR (Q96EP1)
E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR)
Gene: CHFR

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 22493164
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf-C3HC4_2, zf-C3HC4_2~zf_C2HC_14
Common GO terms GO:0000209 - protein polyubiquitination
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 664
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024