Interactor 1: PLK4 (O00444)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase 18) (Serine/threonine-protein kinase Sak)
Gene: PLK4

Interactor 2: NEK7 (Q8TDX7)
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)
Gene: NEK7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31762063
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000922 - spindle pole
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005813 - centrosome
GO:0006468 - protein phosphorylation
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 970
Hs

1 302
+ At
+ At
+ Zm
+ At
+ At
+ At
+ At
+ At
+ At
+ Zm
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024