HitPredict

Interactor 1: CYFP2 (Q96F07)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: CYFIP2

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Abi_HHR~FragX_IP
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031209 - SCAR complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 513
+	Hs
		1224632 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Mm
		1131118 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		ABI1_MOUSE (1-513): 2.82e-100: 312: 60.04
+	Hs
		1184628 CYFP1_HUMAN (1-1277): 0: 2040: 85.92		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Mm
		1186395 CYFP1_MOUSE (1-1277): 0: 2032: 85.68		ABI1_MOUSE (1-513): 2.82e-100: 312: 60.04
+	Hs
		1184662 CYFP1_HUMAN (1-1277): 0: 2040: 85.92		ABI2_HUMAN (1-513): 1.82e-91: 290: 100.00
+	Mm
		1131060 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		SRC8_MOUSE (272-507): 8.45e-33: 133: 17.80
+	Hs
		1290813 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		ABI3_HUMAN (262-507): 4.36e-17: 84.9: 23.17
+	Hs
		924782 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Mm
		913886 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		ABI2_MOUSE (259-513): 1.38e-28: 119: 67.95
+	Dm
		1365310 CYFIP_DROME (1-1277): 0: 1898: 64.75		Q9Y0S9_DROME (1-507): 5.88e-73: 240: 34.91
+	Dd
		1122367 PIRA_DICDI (7-1249): 0: 1445: 36.98		ABIA_DICDI (3-255): 4.63e-29: 119: 19.46