Interactor 1: DPH3 (Q96FX2)
Diphthamide biosynthesis protein 3 (CSL-type zinc finger-containing protein 2) (DelGEF-interacting protein 1) (DelGIP1)
Gene: DPH3
Interactor 2: SRGEF (Q9UGK8)
Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein)
Gene: SERGEF
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 1.00 | 0.928 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 28514442, 33961781, 14980502, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RCC1~zf-CSL |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0050709 - negative regulation of protein secretion |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
