Interactor 1: CHMP6 (Q96FZ7)
Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (Vps20) (hVps20)
Gene: CHMP6

Interactor 2: VPS25 (Q9BRG1)
Vacuolar protein-sorting-associated protein 25 (hVps25) (Dermal papilla-derived protein 9) (ELL-associated protein of 20 kDa) (ESCRT-II complex subunit VPS25)
Gene: VPS25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 32296183, 16371348, 16973552, 33961781, 14505570, 16730941, 15511219, unassigned1304, 16856878
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007175 - negative regulation of epidermal growth factor-activated receptor activity
GO:0010008 - endosome membrane
GO:0016236 - macroautophagy
GO:0036258 - multivesicular body assembly
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 201
Hs

1 176
+ At
+ Ce
+ At
+ Dm
+ Dm
+ Sc
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024