Interactor 1: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 15249581, 29568061, 31586073, 22371557, 21658950, 18710370
Identification Methods affinity chromatography technology, proximity labelling technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
and 50 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 344
Hs

1 344
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Last updated: 15 Jul 2024