HitPredict

Interactor 1: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 7388
+	Hs
		885294 AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		551616 AKT1_HUMAN (3-343): 6.77e-137: 399: 28.53		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		1068636 AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		551805 AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Rn
		1144340 AKT3_RAT (3-343): 9.7e-137: 398: 28.05		SPTN2_RAT (3436-4815): 6.61e-11: 72.1: 9.65
+	Hs
		809157 AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98