HitPredict

Interactor 1: DCNL1 (Q96GG9)
DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)
Gene: DCUN1D1

Interactor 2: KLH21 (Q9UJP4)
Kelch-like protein 21
Gene: KLHL21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0097602 - cullin family protein binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 259 Hs			1 597
+	Hs
		1292398 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLHL9_HUMAN (12-558): 3.24e-148: 443: 27.18
+	Hs
		1121487 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH26_HUMAN (12-548): 1.9e-58: 207: 29.51
+	Hs
		299530 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH18_HUMAN (403-597): 1.79e-43: 165: 23.65
+	Hs
		299519 DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21		KLH18_HUMAN (403-597): 1.79e-43: 165: 23.65
+	Hs
		1292409 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH20_HUMAN (452-595): 1.94e-32: 134: 22.52
+	Hs
		1292400 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH13_HUMAN (479-595): 2.96e-24: 109: 19.84
+	Hs
		1161488 DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21		KLH24_HUMAN (436-594): 1.4e-22: 104: 15.39
+	Hs
		1120800 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH12_HUMAN (499-595): 2.13e-13: 74.8: 21.00
+	Hs
		1292397 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLHL8_HUMAN (254-380): 3.85e-12: 71: 19.69
+	Hs
		1239683 DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00		KLH23_HUMAN (236-382): 3.67e-10: 64.8: 19.46