Protein: OSTM1
Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit)

Gene: OSTM1
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q86WC4

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0030316 - osteoclast differentiation
GO:0030321 - transepithelial chloride transport
GO:0034707 - chloride channel complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

907811

CLCN7
H(+)/Cl(-) exchange transporter 7

6

1

Small-scale

0.949

High

125520

LEG9
Galectin-9

3

2

High-throughput

0.667

High

127365

LEG8
Galectin-8

3

2

High-throughput

0.667

High

609731

LEG3
Galectin-3

3

2

High-throughput

0.667

High

1292396

BIRC7
Baculoviral IAP repeat-containing protein 7

3

2

High-throughput

0.667

High

1022740

XIAP
E3 ubiquitin-protein ligase XIAP

2

2

High-throughput

0.601

High

1107424

BIRC2
Baculoviral IAP repeat-containing protein 2

2

2

High-throughput

0.601

High

1090760

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.576

High

1224746

RN213
E3 ubiquitin-protein ligase RNF213

2

0

High-throughput

0.576

High

1292415

EXOS3
Exosome complex component RRP40

1

0

Small-scale

0.537

High

231722

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.536

High

408094

TBB4A
Tubulin beta-4A chain

1

5

High-throughput

0.536

High

457532

TBB5
Tubulin beta chain

1

5

High-throughput

0.536

High

997012

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.536

High

997409

TBB4B
Tubulin beta-4B chain

1

5

High-throughput

0.536

High

1112248

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.536

High

1259316

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.536

High

564011

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

292674

RENR
Renin receptor

1

0

High-throughput

0.513

High

658729

JAK1
Tyrosine-protein kinase JAK1

1

0

High-throughput

0.513

High

843723

HD
Huntingtin

1

0

High-throughput

0.513

High

884664

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

977745

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.513

High

1289003

NLRX1
NLR family member X1

1

0

High-throughput

0.513

High

1292411

ZWILC
Protein zwilch homolog

1

0

High-throughput

0.513

High

1292417

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.513

High

1292421

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

0

High-throughput

0.513

High

1292423

FBX2
F-box only protein 2

1

0

High-throughput

0.513

High

1292427

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

0

High-throughput

0.513

High

424952

ADT2
ADP/ATP translocase 2

1

4

High-throughput

0.489

High

552035

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.489

High

552302

ADT3
ADP/ATP translocase 3

1

4

High-throughput

0.489

High

1108590

TBB3
Tubulin beta-3 chain

1

5

High-throughput

0.489

High

1210694

KMCP1
Kidney mitochondrial carrier protein 1

1

4

High-throughput

0.489

High

1292401

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.489

High

1292403

TBB6
Tubulin beta-6 chain

1

5

High-throughput

0.489

High

1292404

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

4

High-throughput

0.489

High

1292405

TBB2B
Tubulin beta-2B chain

1

5

High-throughput

0.489

High

1292418

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

1

High-throughput

0.489

High

890635

RGS19
Regulator of G-protein signaling 19

1

2

Small-scale

0.481

High

1292387

GPSM1
G-protein-signaling modulator 1

1

0

Small-scale

0.480

High

560440

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

1031441

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1292413

EXOS4
Exosome complex component RRP41

1

1

Small-scale

0.479

High

1292414

EXOS5
Exosome complex component RRP46

1

1

Small-scale

0.479

High

562182

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.458

High

1118298

EXOS2
Exosome complex component RRP4

1

0

Small-scale

0.458

High

1102722

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

1

High-throughput

0.445

High

1292399

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

1

High-throughput

0.445

High

303162

RGS20
Regulator of G-protein signaling 20

1

2

Small-scale

0.439

High

1292422

RGS17
Regulator of G-protein signaling 17

1

2

Small-scale

0.439

High

341256

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

0

High-throughput

0.426

High

637920

NF1
Neurofibromin

1

0

High-throughput

0.426

High

1219163

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.426

High

1292416

MDN1
Midasin

1

0

High-throughput

0.426

High

1292425

MYRF
Myelin regulatory factor

1

0

High-throughput

0.426

High

522692

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

High-throughput

0.407

High

1292392

S2529
Mitochondrial basic amino acids transporter

1

5

High-throughput

0.407

High

1292389

F177A
Protein FAM177A1

2

0

High-throughput

0.318

High

1212717

TMTC4
Protein O-mannosyl-transferase TMTC4

2

0

High-throughput

0.313

High

1292419

UFSP2
Ufm1-specific protease 2

2

0

High-throughput

0.313

High

50609

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.279

Low

135815

RTCA
RNA 3'-terminal phosphate cyclase

1

0

High-throughput

0.279

Low

351706

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.279

Low

956927

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.279

Low

1103830

TARB1
tRNA

1

0

High-throughput

0.279

Low

1108796

ASAH1
Acid ceramidase

1

0

High-throughput

0.279

Low

1109469

ATR
Serine/threonine-protein kinase ATR

1

0

High-throughput

0.279

Low

1135902

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

High-throughput

0.279

Low

1160409

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

1235406

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.279

Low

1292390

INT1
Integrator complex subunit 1

1

0

High-throughput

0.279

Low

1292391

GUF1
Translation factor GUF1, mitochondrial

1

0

High-throughput

0.279

Low

1292393

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

0

High-throughput

0.279

Low

1292394

PPTC7
Protein phosphatase PTC7 homolog

1

0

High-throughput

0.279

Low

1292400

F118B
Protein FAM118B

1

0

High-throughput

0.279

Low

1292402

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.279

Low

1292406

SFXN3
Sideroflexin-3

1

0

High-throughput

0.279

Low

1292409

NSUN3
tRNA

1

0

High-throughput

0.279

Low

1292420

RTEL1
Regulator of telomere elongation helicase 1

1

0

High-throughput

0.279

Low

1292424

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low

1292426

FLVC1
Choline/ethanolamine transporter FLVCR1

1

0

High-throughput

0.279

Low

892692

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low

1292395

SYNE2
Nesprin-2

1

0

High-throughput

0.249

Low

1292410

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.249

Low

1292412

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.249

Low

848968

MAGAC
Melanoma-associated antigen 12

1

0

High-throughput

0.232

Low

1211167

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

1230746

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.232

Low

1242140

PDXD2
Putative pyridoxal-dependent decarboxylase domain-containing protein 2

1

0

High-throughput

0.232

Low

1252799

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.232

Low

1286976

DAAM2
Disheveled-associated activator of morphogenesis 2

1

0

High-throughput

0.232

Low

1292388

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.232

Low

1292397

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.232

Low

1292398

RUSF1
RUS family member 1

1

0

High-throughput

0.232

Low

1292407

INT2
Integrator complex subunit 2

1

0

High-throughput

0.232

Low

1292408

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025