HitPredict

Interactor 1: P85B (O00459)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: PIK3R2

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 728 Hs			1 232
+	Hs
		129263 P85B_HUMAN (1-728): 0: 549: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		129260 P85B_HUMAN (1-728): 0: 549: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		129249 P85B_HUMAN (1-728): 0: 549: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		129270 P85B_HUMAN (1-728): 0: 549: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		129259 P85B_HUMAN (1-728): 0: 549: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		129190 P85B_HUMAN (1-728): 0: 549: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		129262 P85B_HUMAN (1-728): 0: 549: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		129275 P85B_HUMAN (1-728): 0: 549: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		129267 P85B_HUMAN (1-728): 0: 549: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120196 P85B_HUMAN (1-728): 0: 549: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		129338 P85B_HUMAN (1-728): 0: 549: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		914255 P55G_HUMAN (312-722): 1.53e-103: 326: 71.85		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		900751 P55G_HUMAN (312-722): 1.53e-103: 326: 71.85		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		855778 VAV2_HUMAN (561-717): 1.41e-31: 134: 21.18		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		789051 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		855782 VAV2_HUMAN (561-717): 1.41e-31: 134: 21.18		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		789055 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		789050 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		855779 VAV2_HUMAN (561-717): 1.41e-31: 134: 21.18		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		545245 ABL2_HUMAN (545-725): 5.17e-31: 132: 25.28		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22