Protein: KAPCG
cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)

Gene: KAPCG, PRKACG
Organism: Homo sapiens
Interactions: 111
UniProt ID: P22612

Gene Ontology (top 5):
GO:0003091 - renal water homeostasis
GO:0004674 - protein serine/threonine kinase activity
GO:0004691 - cAMP-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

650525

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

4

20

High-throughput

0.903

High

530995

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

3

20

High-throughput

0.861

High

605550

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

3

14

High-throughput

0.861

High

507079

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

7

High-throughput

0.811

High

568756

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

2

20

High-throughput

0.811

High

650520

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

14

High-throughput

0.811

High

650524

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

20

High-throughput

0.811

High

650561

GP161
G-protein coupled receptor 161

2

4

High-throughput

0.726

High

650542

CDK17
Cyclin-dependent kinase 17

1

8

High-throughput

0.698

High

256580

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.691

High

258762

DNJA2
DnaJ homolog subfamily A member 2

1

13

High-throughput

0.691

High

274465

DNJB6
DnaJ homolog subfamily B member 6

1

14

High-throughput

0.691

High

461152

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.691

High

468074

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.691

High

650522

DNJB1
DnaJ homolog subfamily B member 1

1

13

High-throughput

0.691

High

650526

DNJA1
DnaJ homolog subfamily A member 1

1

13

High-throughput

0.691

High

650543

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

20

High-throughput

0.691

High

650545

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

19

High-throughput

0.691

High

650548

CIRBP
Cold-inducible RNA-binding protein

1

10

High-throughput

0.691

High

650550

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

20

High-throughput

0.691

High

650552

DDB1
DNA damage-binding protein 1

1

3

High-throughput

0.691

High

650553

CDC37
Hsp90 co-chaperone Cdc37

1

11

High-throughput

0.691

High

650566

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

10

High-throughput

0.691

High

650570

CCNL2
Cyclin-L2

1

3

High-throughput

0.691

High

650571

DNJC7
DnaJ homolog subfamily C member 7

1

8

High-throughput

0.691

High

650577

CLPB
Mitochondrial disaggregase

1

2

High-throughput

0.691

High

650593

IPKG
cAMP-dependent protein kinase inhibitor gamma

1

2

High-throughput

0.691

High

650557

AKA28
A-kinase anchor protein 14

3

2

High-throughput

0.667

High

650565

RYR2
Ryanodine receptor 2

1

12

Small-scale

0.647

High

536504

HSP7C
Heat shock cognate 71 kDa protein

2

6

High-throughput

0.628

High

650521

AKAP5
A-kinase anchor protein 5

2

4

High-throughput

0.628

High

650541

RT15
Small ribosomal subunit protein uS15m

2

1

High-throughput

0.628

High

650549

NUCG
Endonuclease G, mitochondrial

2

1

High-throughput

0.628

High

650555

MYOME
Myomegalin

2

18

High-throughput

0.628

High

650564

AKAP1
A-kinase anchor protein 1, mitochondrial

2

5

High-throughput

0.628

High

650575

AKAP9
A-kinase anchor protein 9

2

16

High-throughput

0.628

High

650586

AKA7G
A-kinase anchor protein 7 isoform gamma

2

4

High-throughput

0.628

High

424354

HMGN1
Non-histone chromosomal protein HMG-14

2

1

Small-scale

0.619

High

240759

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.618

High

332870

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

4

High-throughput

0.574

High

124736

AIP
AH receptor-interacting protein

1

20

High-throughput

0.536

High

165009

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

2

High-throughput

0.536

High

650538

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.536

High

650539

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.536

High

650540

PRKDC
DNA-dependent protein kinase catalytic subunit

1

17

High-throughput

0.536

High

186318

RA51B
DNA repair protein RAD51 homolog 2

1

2

High-throughput

0.536

High

243890

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

11

High-throughput

0.536

High

315119

RECQ4
ATP-dependent DNA helicase Q4

1

12

High-throughput

0.536

High

325684

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

High-throughput

0.536

High

536314

MTAP2
Microtubule-associated protein 2

1

14

High-throughput

0.536

High

610529

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.536

High

650527

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.536

High

650528

TIMP3
Metalloproteinase inhibitor 3

1

1

High-throughput

0.536

High

650530

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

650531

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.536

High

650532

F10A1
Hsc70-interacting protein

1

20

High-throughput

0.536

High

650533

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.536

High

650534

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.536

High

650535

PPP5
Serine/threonine-protein phosphatase 5

1

15

High-throughput

0.536

High

650536

MLF1
Myeloid leukemia factor 1

1

2

High-throughput

0.536

High

650537

DYL1
Dynein light chain 1, cytoplasmic

1

5

High-throughput

0.536

High

650551

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

650558

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.536

High

650567

DYL2
Dynein light chain 2, cytoplasmic

1

5

High-throughput

0.536

High

650572

NP1L4
Nucleosome assembly protein 1-like 4

1

2

High-throughput

0.536

High

650573

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.536

High

650579

RPAP3
RNA polymerase II-associated protein 3

1

7

High-throughput

0.536

High

650582

SAS10
Something about silencing protein 10

1

2

High-throughput

0.536

High

650584

RNF12
E3 ubiquitin-protein ligase RLIM

1

8

High-throughput

0.536

High

650588

AKA11
A-kinase anchor protein 11

1

2

High-throughput

0.536

High

650590

AKP8L
A-kinase anchor protein 8-like

1

3

High-throughput

0.536

High

650591

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

High-throughput

0.536

High

650592

MAGD2
Melanoma-associated antigen D2

1

4

High-throughput

0.536

High

650594

SGT1
Protein SGT1 homolog

1

6

High-throughput

0.536

High

650595

AP1M2
AP-1 complex subunit mu-2

1

3

High-throughput

0.536

High

421508

A4
Amyloid-beta precursor protein

1

8

High-throughput

0.515

High

650523

CALL3
Calmodulin-like protein 3

1

1

High-throughput

0.514

High

326133

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.513

High

480032

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

601561

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

650554

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.513

High

650569

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.513

High

650574

SPI2A
Spindlin-2A

1

0

High-throughput

0.513

High

650578

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

650580

ROP1A
Ropporin-1A

1

0

High-throughput

0.513

High

650581

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.513

High

650585

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.513

High

650589

AGO2
Protein argonaute-2

1

0

High-throughput

0.513

High

481430

STP1
Spermatid nuclear transition protein 1

1

2

Small-scale

0.501

High

650544

STP2
Nuclear transition protein 2

1

2

Small-scale

0.501

High

650559

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

0

High-throughput

0.493

High

182081

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.489

High

650547

MOGS
Mannosyl-oligosaccharide glucosidase

1

1

High-throughput

0.489

High

650560

TTC9C
Tetratricopeptide repeat protein 9C

1

20

High-throughput

0.489

High

650546

CUL3
Cullin-3

1

4

High-throughput

0.479

High

128777

MEN1
Menin

1

0

High-throughput

0.458

High

529083

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.445

High

575111

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.445

High

650529

HUTH
Histidine ammonia-lyase

1

1

High-throughput

0.445

High

627108

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.426

High

650556

FBX50
F-box only protein 50

1

0

High-throughput

0.426

High

650587

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

0

High-throughput

0.426

High

224408

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

4

High-throughput

0.407

High

650568

C170L
Cep170-like protein

1

2

High-throughput

0.407

High

547731

CETP
Cholesteryl ester transfer protein

1

0

High-throughput

0.282

High

124235

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

209372

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

0

High-throughput

0.279

Low

650563

LIPH
Lipase member H

1

0

High-throughput

0.279

Low

650583

TBCC1
TBCC domain-containing protein 1

1

0

High-throughput

0.279

Low

650562

POF1B
Protein POF1B

1

0

High-throughput

0.232

Low

650576

GDAH
Guanidino acid hydrolase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025