HitPredict

Interactor 1: ACY3 (Q96HD9)
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (EC 3.5.1.114) (Acylase III) (Aminoacylase-3) (ACY-3) (Aspartoacylase-2) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1)
Gene: ACY3

Interactor 2: ACY3 (Q96HD9)
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (EC 3.5.1.114) (Acylase III) (Aminoacylase-3) (ACY-3) (Aspartoacylase-2) (Hepatitis C virus core-binding protein 1) (HCBP1) (HCV core-binding protein 1)
Gene: ACY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.785

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	AstE_AspA~AstE_AspA
Common GO terms	GO:0004046 - aminoacylase activity GO:0005829 - cytosol GO:0016324 - apical plasma membrane GO:0016788 - hydrolase activity, acting on ester bonds GO:0046872 - metal ion binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 319 Hs			1 319
+	Hs
		799454 ACY2_HUMAN (1-308): 0: 541: 44.81		ACY2_HUMAN (1-308): 0: 541: 44.81
+	Hs
		799459 ACY2_HUMAN (1-308): 0: 541: 44.81		ACY3_HUMAN (1-319): 0: 533: 100.00
+	Rn
		1351686 ACY2_RAT (1-308): 0: 530: 45.13		ACY2_RAT (1-308): 0: 530: 45.13
+	Mm
		1265168 ACY3_MOUSE (1-313): 0: 519: 69.97		ACY3_MOUSE (1-313): 0: 519: 69.97