HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29176576
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 685
+	Hs
		475684 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476627 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475691 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475328 RO52_HUMAN (32-468): 2.83e-73: 243: 11.19		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476299 TRAF4_HUMAN (29-551): 2.98e-73: 243: 23.32		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475297 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476418 TRI39_HUMAN (36-468): 6.07e-67: 227: 9.34		UBC_HUMAN (1-685): 0: 846: 100.00
+	Xl
		1186351 NF7B_XENLA (5-483): 3.04e-64: 222: 10.91		Q7SY79_XENLA (77-685): 0: 744: 99.84
+	Mm
		476671 RO52_MOUSE (31-468): 2.74e-74: 245: 11.57		UBB_MOUSE (457-685): 2.3e-86: 275: 99.56
+	Rn
		88507 D3Z9G0_RAT (2-556): 4.02e-125: 380: 40.56		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		78208 B5DFH7_RAT (28-554): 1.75e-98: 309: 32.03		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		397944 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		475011 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		924227 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		924236 RO52_MOUSE (31-468): 2.74e-74: 245: 11.57		RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00
+	Hs
		475253 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Mm
		476831 RO52_MOUSE (31-468): 2.74e-74: 245: 11.57		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476826 TRAF4_MOUSE (29-551): 3.29e-72: 240: 22.95		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		475013 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		475134 TRI11_HUMAN (34-468): 2.85e-72: 240: 13.01		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70