Protein: BPTF
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)

Gene: BPTF
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q12830

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001892 - embryonic placenta development
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

998255

H31
Histone H3.1

4

20

Small-scale

0.873

High

1016810

H33
Histone H3.3

3

20

Small-scale

0.853

High

501974

H2AZ
Histone H2A.Z

2

20

High-throughput

0.789

High

939310

EIF3B
Eukaryotic translation initiation factor 3 subunit B

2

20

High-throughput

0.754

High

1086762

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

20

High-throughput

0.754

High

1066275

RBBP4
Histone-binding protein RBBP4

7

20

Small-scale

0.749

High

1086774

H31T
Histone H3.1t

2

20

Small-scale

0.738

High

1086773

RBBP7
Histone-binding protein RBBP7

6

20

Small-scale

0.732

High

1086788

BAP18
BPTF-associated chromatin complex component 1

5

4

High-throughput

0.709

High

703301

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

4

20

Small-scale

0.699

High

338830

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.691

High

1086775

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

1086783

H32
Histone H3.2

1

20

Small-scale

0.681

High

1086767

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.665

High

1086800

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.665

High

243614

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

3

20

Small-scale

0.656

High

979567

H4
Histone H4

2

20

Small-scale

0.654

High

1086813

DPY30
Protein dpy-30 homolog

3

3

Small-scale

0.651

High

158433

RFXK
DNA-binding protein RFXANK

2

20

High-throughput

0.628

High

1086831

HSPB7
Heat shock protein beta-7

2

10

High-throughput

0.628

High

210269

PHF1
PHD finger protein 1

1

10

High-throughput

0.618

High

259864

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.618

High

274317

SIN3B
Paired amphipathic helix protein Sin3b

1

4

High-throughput

0.618

High

277663

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.618

High

316826

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.618

High

591619

H2AX
Histone H2AX

1

20

High-throughput

0.618

High

674149

BRD2
Bromodomain-containing protein 2

1

18

High-throughput

0.618

High

883523

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

980728

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

1086752

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.618

High

1086756

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.618

High

1086758

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.618

High

1086776

ARI4B
AT-rich interactive domain-containing protein 4B

1

18

High-throughput

0.618

High

1086794

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

High-throughput

0.618

High

1086799

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.618

High

1086807

PHF12
PHD finger protein 12

1

20

High-throughput

0.618

High

1086808

SIN3A
Paired amphipathic helix protein Sin3a

1

4

High-throughput

0.618

High

1086811

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.618

High

1086837

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

High-throughput

0.618

High

1086838

MTF2
Metal-response element-binding transcription factor 2

1

10

High-throughput

0.618

High

224109

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

2

11

High-throughput

0.611

High

940385

MAZ
Myc-associated zinc finger protein

2

13

Small-scale

0.609

High

911224

IMA5
Importin subunit alpha-5

2

19

High-throughput

0.601

High

285242

EED
Polycomb protein EED

2

20

High-throughput

0.584

High

648356

USF1
Upstream stimulatory factor 1

2

20

Small-scale

0.584

High

1086763

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1086766

SUZ12
Polycomb protein SUZ12

2

4

High-throughput

0.584

High

1086771

EZH2
Histone-lysine N-methyltransferase EZH2

2

20

High-throughput

0.584

High

371886

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.571

High

346985

BAG2
BAG family molecular chaperone regulator 2

1

8

High-throughput

0.536

High

378489

IL1A
Interleukin-1 alpha

1

2

High-throughput

0.536

High

487242

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.536

High

788000

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

8

High-throughput

0.536

High

848247

MAGA3
Melanoma-associated antigen 3

1

13

High-throughput

0.536

High

1029666

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

1086755

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

4

High-throughput

0.536

High

1086761

SMC1A
Structural maintenance of chromosomes protein 1A

1

20

High-throughput

0.536

High

1086781

L2GL2
LLGL scribble cell polarity complex component 2

1

12

High-throughput

0.536

High

1086790

K2C78
Keratin, type II cytoskeletal 78

1

4

High-throughput

0.536

High

1086791

ZN784
Zinc finger protein 784

1

16

High-throughput

0.536

High

1086836

TPX2
Targeting protein for Xklp2

1

6

High-throughput

0.536

High

1086839

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.536

High

1086759

KEAP1
Kelch-like ECH-associated protein 1

1

6

Small-scale

0.527

High

977217

RS4X
Small ribosomal subunit protein eS4, X isoform

1

2

High-throughput

0.515

High

1086780

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1086757

SQSTM
Sequestosome-1

1

5

High-throughput

0.508

High

964249

SUMO2
Small ubiquitin-related modifier 2

1

13

High-throughput

0.501

High

1014489

SMAD3
Mothers against decapentaplegic homolog 3

1

20

Small-scale

0.501

High

1086770

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.501

High

1086772

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.501

High

1086818

N62CL
Nucleoporin-62 C-terminal-like protein

1

6

High-throughput

0.489

High

66846

DUXA
Double homeobox protein A

1

20

High-throughput

0.479

High

129023

MEN1
Menin

1

4

High-throughput

0.479

High

142970

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

155299

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

5

High-throughput

0.479

High

157297

CTRO
Citron Rho-interacting kinase

1

15

High-throughput

0.479

High

168233

HAT1
Histone acetyltransferase type B catalytic subunit

1

3

High-throughput

0.479

High

190891

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

19

High-throughput

0.479

High

282243

SAP30
Histone deacetylase complex subunit SAP30

1

2

High-throughput

0.479

High

285646

BAF
Barrier-to-autointegration factor

1

4

High-throughput

0.479

High

339731

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

352122

MBD3
Methyl-CpG-binding domain protein 3

1

10

High-throughput

0.479

High

363197

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

413723

P53
Cellular tumor antigen p53

1

20

High-throughput

0.479

High

442931

PRGR
Progesterone receptor

1

20

Small-scale

0.479

High

473951

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

519495

MYBB
Myb-related protein B

1

11

High-throughput

0.479

High

558078

XRCC6
X-ray repair cross-complementing protein 6

1

16

High-throughput

0.479

High

577434

ETS1
Protein C-ets-1

1

20

High-throughput

0.479

High

581653

MYOD1
Myoblast determination protein 1

1

20

High-throughput

0.479

High

588563

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

606695

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.479

High

623308

RO52
E3 ubiquitin-protein ligase TRIM21

1

9

High-throughput

0.479

High

675481

TYY1
Transcriptional repressor protein YY1

1

20

High-throughput

0.479

High

685176

PAX6
Paired box protein Pax-6

1

16

High-throughput

0.479

High

695318

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

697091

APEX1
DNA repair nuclease/redox regulator APEX1

1

5

High-throughput

0.479

High

703129

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

738973

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

768058

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

775835

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

799046

BRCA1
Breast cancer type 1 susceptibility protein

1

18

High-throughput

0.479

High

833930

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

851537

GATA4
Transcription factor GATA-4

1

20

High-throughput

0.479

High

862079

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

872263

SOX2
Transcription factor SOX-2

1

20

Small-scale

0.479

High

886803

CEBPA
CCAAT/enhancer-binding protein alpha

1

20

High-throughput

0.479

High

904651

MECP2
Methyl-CpG-binding protein 2

1

20

High-throughput

0.479

High

944641

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

986375

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

11

High-throughput

0.479

High

1008699

RED1
Double-stranded RNA-specific editase 1

1

13

High-throughput

0.479

High

1033663

PO5F1
POU domain, class 5, transcription factor 1

1

17

High-throughput

0.479

High

1037860

HEN1
Helix-loop-helix protein 1

1

18

High-throughput

0.479

High

1057988

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

4

High-throughput

0.479

High

1086751

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1086753

CAF1A
Chromatin assembly factor 1 subunit A

1

11

High-throughput

0.479

High

1086754

CAF1B
Chromatin assembly factor 1 subunit B

1

20

High-throughput

0.479

High

1086760

DOCK1
Dedicator of cytokinesis protein 1

1

10

High-throughput

0.479

High

1086764

CUL7
Cullin-7

1

9

High-throughput

0.479

High

1086765

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.479

High

1086768

PDIA6
Protein disulfide-isomerase A6

1

15

High-throughput

0.479

High

1086769

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1086778

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

5

High-throughput

0.479

High

1086779

LIN9
Protein lin-9 homolog

1

1

High-throughput

0.479

High

1086782

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1086784

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

14

High-throughput

0.479

High

1086785

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

1086786

TAXB1
Tax1-binding protein 1

1

17

High-throughput

0.479

High

1086787

P66A
Transcriptional repressor p66-alpha

1

14

High-throughput

0.479

High

1086789

SMC5
Structural maintenance of chromosomes protein 5

1

20

High-throughput

0.479

High

1086793

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1086795

ZN296
Zinc finger protein 296

1

17

High-throughput

0.479

High

1086796

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

1086797

P66B
Transcriptional repressor p66-beta

1

14

High-throughput

0.479

High

1086798

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1086805

Z512B
Zinc finger protein 512B

1

20

High-throughput

0.479

High

1086806

PWP2A
PWWP domain-containing protein 2A

1

18

High-throughput

0.479

High

1086809

TBX5
T-box transcription factor TBX5

1

18

High-throughput

0.479

High

1086810

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1086812

NSD3
Histone-lysine N-methyltransferase NSD3

1

20

Small-scale

0.479

High

1086814

BC11B
B-cell lymphoma/leukemia 11B

1

13

High-throughput

0.479

High

1086815

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1086816

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

1086817

BC11A
BCL11 transcription factor A

1

13

High-throughput

0.479

High

1086819

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

1086820

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

5

High-throughput

0.479

High

1086822

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

17

High-throughput

0.479

High

1086823

RAD18
E3 ubiquitin-protein ligase RAD18

1

4

High-throughput

0.479

High

1086824

DCA13
DDB1- and CUL4-associated factor 13

1

20

Small-scale

0.479

High

1086825

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

1086827

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

6

High-throughput

0.479

High

1086829

ZN219
Zinc finger protein 219

1

12

High-throughput

0.479

High

1086830

MBD2
Methyl-CpG-binding domain protein 2

1

10

High-throughput

0.479

High

1086832

ZRAN1
Ubiquitin thioesterase ZRANB1

1

17

High-throughput

0.479

High

1086833

HMGX4
HMG domain-containing protein 4

1

20

High-throughput

0.479

High

1086834

XPO7
Exportin-7

1

15

High-throughput

0.479

High

1086777

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

1086792

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.458

High

1086803

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

1086804

SNF8
Vacuolar-sorting protein SNF8

1

0

High-throughput

0.458

High

1086821

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.458

High

114551

H0YIS7
BPTF-associated chromatin complex component 1

1

4

High-throughput

0.445

High

391237

FRIL
Ferritin light chain

1

2

High-throughput

0.445

High

903891

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.437

High

1086835

HECD1
E3 ubiquitin-protein ligase HECTD1

1

18

High-throughput

0.437

High

1086801

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1086826

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

1086828

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.249

Low

1086802

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025