HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TNR8 (P28908)
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene: TNFRSF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	8999898, 9511754, 11971184
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 595
+	Hs
		129607 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR11_HUMAN (30-202): 4.53e-45: 170: 22.10
+	Hs
		129526 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82
+	Mm
		838552 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR3_MOUSE (13-226): 6.17e-46: 169: 21.33
+	Hs
		129584 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR14_HUMAN (3-186): 5.8e-44: 159: 23.94
+	Hs
		129536 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR3_HUMAN (3-194): 8.37e-42: 158: 25.87
+	Hs
		129532 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR5_HUMAN (3-247): 2.73e-38: 144: 16.85
+	Mm
		192584 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR11_MOUSE (5-202): 3.51e-38: 151: 22.82
+	Mm
		936208 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR14_MOUSE (24-190): 8.16e-35: 134: 22.99
+	Hs
		129538 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR4_HUMAN (39-231): 5.59e-30: 121: 17.16
+	Hs
		129553 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR9_HUMAN (45-213): 4.17e-27: 112: 16.38
+	Hs
		591320 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1B_HUMAN (12-239): 1.19e-49: 180: 26.16
+	Mm
		838553 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR3_MOUSE (13-226): 6.17e-46: 169: 21.33
+	Hs
		436620 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR16_HUMAN (29-243): 1.87e-43: 162: 19.82
+	Hs
		129533 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		CD27_HUMAN (23-123): 1.5e-19: 90.6: 21.15
+	Mm
		192587 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR11_MOUSE (5-202): 3.51e-38: 151: 22.82
+	Hs
		584394 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1A_HUMAN (22-194): 7.64e-40: 153: 19.02
+	Mm
		648958 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR5_MOUSE (5-247): 7.52e-38: 143: 15.07
+	Mm
		812913 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR4_MOUSE (39-233): 3.85e-34: 132: 16.02
+	Hs
		632265 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR6_HUMAN (41-151): 4.94e-29: 119: 23.08
+	Mm
		591448 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR9_MOUSE (45-191): 7.51e-24: 102: 16.99