HitPredict

Interactor 1: LRIQ1 (Q96JM4)
Leucine-rich repeat and IQ domain-containing protein 1
Gene: LRRIQ1

Interactor 2: LGR4 (Q9BXB1)
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)
Gene: LGR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8, LRR_8~LRRNT
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1722 Hs			1 951
+	At
		1114706 PXL1_ARATH (785-1345): 3.99e-93: 328: 14.19		ERECT_ARATH (1-581): 3.45e-126: 407: 20.31
+	At
		1325020 PXL1_ARATH (785-1345): 3.99e-93: 328: 14.19		PXL1_ARATH (1-550): 1.27e-125: 407: 19.04
+	At
		1114682 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		ERECT_ARATH (1-581): 3.45e-126: 407: 20.31
+	At
		1114705 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		FLS2_ARATH (15-505): 4.99e-104: 352: 20.32
+	At
		221789 RGI1_ARATH (756-1359): 4.1e-88: 316: 15.27		BAME1_ARATH (57-586): 6.25e-98: 332: 17.65
+	At
		221761 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		BAME1_ARATH (57-586): 6.25e-98: 332: 17.65
+	At
		84605 RGI1_ARATH (756-1359): 4.1e-88: 316: 15.27		RGI3_ARATH (1-398): 9.93e-92: 316: 21.90
+	At
		84593 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		RGI3_ARATH (1-398): 9.93e-92: 316: 21.90
+	At
		1114685 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		ERL2_ARATH (154-753): 4.57e-77: 273: 14.31
+	At
		84588 BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57		RGI3_ARATH (1-398): 9.93e-92: 316: 21.90
+	At
		1114702 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		TDR_ARATH (181-586): 2.32e-57: 216: 18.42
+	At
		84466 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		GSO1_ARATH (231-493): 9.58e-50: 193: 16.67
+	At
		85352 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		ERL1_ARATH (1-259): 1.16e-49: 192: 21.76
+	At
		1114713 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		BAME2_ARATH (227-494): 2.07e-46: 182: 17.56
+	At
		1338062 RGI1_ARATH (756-1359): 4.1e-88: 316: 15.27		EMS1_ARATH (261-503): 2.88e-44: 176: 17.53
+	At
		1114712 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		EMS1_ARATH (261-503): 2.88e-44: 176: 17.53
+	At
		84459 BAME1_ARATH (775-1219): 9.59e-71: 260: 12.57		GSO1_ARATH (231-493): 9.58e-50: 193: 16.67
+	At
		1338065 RGI1_ARATH (756-1359): 4.1e-88: 316: 15.27		BRL2_ARATH (265-505): 1.86e-31: 135: 19.69
+	At
		187538 ERECT_ARATH (834-1396): 4.55e-89: 315: 15.35		PXC3_ARATH (285-456): 4.16e-19: 95.1: 19.77