Protein: YPT1
GTP-binding protein YPT1 (Protein YP2) (Rab GTPase YPT1) (Transport GTPase YPT1)

Gene: YPT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 113
UniProt ID: P01123

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0000407 - phagophore assembly site
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376305

GDI1
Rab GDP-dissociation inhibitor

12

20

Small-scale

0.982

High

376282

RAEP
Rab proteins geranylgeranyltransferase component A

6

20

Small-scale

0.952

High

376323

ATG1
Serine/threonine-protein kinase ATG1

3

6

Small-scale

0.876

High

376280

MSS4
Protein DSS4

5

0

Small-scale

0.868

High

376278

HRR25
Casein kinase I homolog HRR25

2

4

Small-scale

0.806

High

376288

TOR1
Serine/threonine-protein kinase TOR1

2

5

Small-scale

0.806

High

376255

SEC4
Ras-related protein SEC4

2

18

High-throughput

0.789

High

376250

YPT1
GTP-binding protein YPT1

2

17

Small-scale

0.778

High

376350

GYP1
GTPase-activating protein GYP1

2

16

Small-scale

0.778

High

376298

YPT31
GTP-binding protein YPT31/YPT8

2

18

Small-scale

0.754

High

376321

YIP1
Protein transport protein YIP1

4

5

Small-scale

0.698

High

376333

SED5
Integral membrane protein SED5

4

12

Small-scale

0.696

High

376328

YIF1
Protein transport protein YIF1

3

3

Small-scale

0.674

High

376266

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

3

Small-scale

0.651

High

376358

ATG11
Autophagy-related protein 11

3

0

Small-scale

0.647

High

376322

YIP4
Protein YIP4

2

5

Small-scale

0.633

High

376315

TRS85
Trafficking protein particle complex III-specific subunit 85

3

0

Small-scale

0.619

High

376254

KAPC
cAMP-dependent protein kinase type 3

1

1

Small-scale

0.618

High

376269

VPS15
Serine/threonine-protein kinase VPS15

1

3

High-throughput

0.618

High

376270

VPS34
Phosphatidylinositol 3-kinase VPS34

1

10

High-throughput

0.618

High

376271

KC11
Casein kinase I homolog 1

1

4

High-throughput

0.618

High

376272

SIS1
Protein SIS1

1

2

High-throughput

0.618

High

376341

TR120
Trafficking protein particle complex II-specific subunit 120

1

1

Small-scale

0.618

High

376338

BET5
Trafficking protein particle complex subunit BET5

1

0

Small-scale

0.614

High

376340

TRS23
Trafficking protein particle complex subunit 23

1

0

Small-scale

0.614

High

376347

ATG23
Autophagy-related protein 23

2

0

Small-scale

0.605

High

376352

ATG9
Autophagy-related protein 9

2

0

Small-scale

0.598

High

376274

USO1
Intracellular protein transport protein USO1

2

5

Small-scale

0.595

High

376291

BET3
Trafficking protein particle complex subunit BET3

2

1

Small-scale

0.595

High

376361

TRS33
Trafficking protein particle complex subunit 33

2

1

Small-scale

0.595

High

376295

ATG8
Autophagy-related protein 8

2

5

High-throughput

0.584

High

376275

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.575

High

376327

PRA1
Prenylated Rab acceptor 1

1

11

Small-scale

0.573

High

376251

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.571

High

376297

TRS20
Trafficking protein particle complex subunit 20

2

0

Small-scale

0.569

High

376307

COG3
Conserved oligomeric Golgi complex subunit 3

1

1

Small-scale

0.561

High

376308

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

376268

SEC22
Protein transport protein SEC22

1

4

Small-scale

0.550

High

376346

ATG17
Autophagy-related protein 17

1

0

Small-scale

0.549

High

376262

ARF1
ADP-ribosylation factor 1

1

18

High-throughput

0.541

High

376285

UBC6
Ubiquitin-conjugating enzyme E2 6

1

1

High-throughput

0.536

High

376332

ALO
D-arabinono-1,4-lactone oxidase

1

0

High-throughput

0.518

High

376281

PEP12
Syntaxin PEP12

1

11

High-throughput

0.508

High

376329

COG6
Conserved oligomeric Golgi complex subunit 6

1

1

High-throughput

0.508

High

376261

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

9

Small-scale

0.501

High

376306

GEA2
ARF guanine-nucleotide exchange factor 2

1

8

Small-scale

0.501

High

376313

ROG3
Protein ROG3

1

1

Small-scale

0.501

High

376317

GEA1
ARF guanine-nucleotide exchange factor 1

1

9

Small-scale

0.501

High

376335

ROD1
Protein ROD1

1

1

Small-scale

0.501

High

376252

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.500

High

376331

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.500

High

376325

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

Small-scale

0.493

High

376273

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.486

High

376354

RBD2
Rhomboid-type serine protease 2

1

0

High-throughput

0.486

High

376267

VPS33
Vacuolar protein sorting-associated protein 33

1

6

Small-scale

0.481

High

376339

TR130
Trafficking protein particle complex II-specific subunit 130

1

1

Small-scale

0.481

High

376311

UFE1
Syntaxin UFE1

1

0

Small-scale

0.480

High

376337

TRS31
Trafficking protein particle complex subunit 31

1

0

Small-scale

0.480

High

376357

LDB19
Protein LDB19

1

0

Small-scale

0.480

High

376253

GAL1
Galactokinase

1

0

High-throughput

0.479

High

376256

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

11

High-throughput

0.479

High

376257

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

5

High-throughput

0.479

High

376264

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

376265

SEC23
Protein transport protein SEC23

1

2

High-throughput

0.479

High

376286

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

376289

ATG19
Autophagy-related protein 19

1

1

Small-scale

0.479

High

376290

YKT6
Synaptobrevin homolog YKT6

1

4

Small-scale

0.479

High

376292

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.479

High

376303

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

376309

SEC24
Protein transport protein SEC24

1

2

High-throughput

0.479

High

376312

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

376318

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

376330

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

376342

SEC13
Protein transport protein SEC13

1

4

High-throughput

0.479

High

376344

RTN1
Reticulon-like protein 1

1

13

Small-scale

0.479

High

376351

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.479

High

376355

ATG34
Autophagy-related protein 34

1

1

Small-scale

0.479

High

376359

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

376283

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

376296

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.458

High

376304

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

376314

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

376316

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

376319

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

376336

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

376360

ATG40
Autophagy-related protein 40

1

0

Small-scale

0.458

High

376259

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.457

High

376334

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

376258

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.445

High

376260

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

376263

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

376300

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

376348

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

11

Small-scale

0.445

High

376353

RRP6
Exosome complex exonuclease RRP6

1

2

Small-scale

0.437

High

376277

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.300

High

376324

YIP5
Protein YIP5

2

0

Small-scale

0.300

High

376356

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.282

High

376293

KTR3
Probable mannosyltransferase KTR3

1

0

High-throughput

0.265

Low

376310

MAD2
Mitotic spindle checkpoint component MAD2

1

0

Small-scale

0.261

Low

376276

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

376279

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

376284

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

376287

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.249

Low

376294

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

376299

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

376301

RRP4
Exosome complex component RRP4

1

0

Small-scale

0.249

Low

376302

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

0

Small-scale

0.249

Low

376320

SPT20
SAGA complex subunit SPT20

1

0

Small-scale

0.249

Low

376326

NRD1
Protein NRD1

1

0

Small-scale

0.249

Low

376343

IVY1
Protein IVY1

1

0

Small-scale

0.249

Low

376345

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

376349

RBX1
RING-box protein HRT1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025