HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TNR9 (Q07011)
Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
Gene: TNFRSF9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15941918
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 255
+	Hs
		129607 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR11_HUMAN (27-202): 2.07e-39: 146: 24.35
+	Mm
		192584 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35
+	Hs
		129536 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR3_HUMAN (24-172): 1.12e-35: 133: 28.24
+	Hs
		129538 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR4_HUMAN (23-184): 3.66e-35: 128: 22.62
+	Mm
		591448 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR9_MOUSE (1-247): 9.28e-58: 186: 56.05
+	Hs
		129532 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR5_HUMAN (27-162): 3.56e-32: 120: 26.62
+	Mm
		838552 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR3_MOUSE (24-164): 2.87e-32: 123: 29.27
+	Mm
		936208 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR14_MOUSE (19-162): 1.53e-30: 116: 29.27
+	Hs
		129584 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR14_HUMAN (19-140): 1.46e-22: 95.2: 26.76
+	Mm
		192587 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR11_MOUSE (27-202): 2.04e-42: 154: 24.35
+	Hs
		129533 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		CD27_HUMAN (24-103): 1.03e-12: 67.9: 31.03
+	Mm
		812913 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR4_MOUSE (27-186): 1.67e-35: 129: 23.49
+	Hs
		591320 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1B_HUMAN (23-186): 1.41e-35: 133: 23.37
+	Hs
		129526 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR16_HUMAN (19-91): 3.12e-10: 61.7: 29.49
+	Mm
		648958 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR5_MOUSE (27-159): 4.69e-33: 123: 28.48
+	Mm
		838553 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR3_MOUSE (24-164): 2.87e-32: 123: 29.27
+	Hs
		639578 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR5_HUMAN (27-162): 3.56e-32: 120: 26.62
+	Hs
		632265 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR6_HUMAN (4-134): 1.12e-22: 96.4: 20.28
+	Hs
		584394 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1A_HUMAN (26-230): 1.12e-20: 92.2: 16.14
+	Hs
		436620 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR16_HUMAN (19-91): 3.12e-10: 61.7: 29.49