HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: DHX58 (Q96C10)
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)
Gene: DHX58

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29661858
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 678
+	Hs
		1024728 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		DHX58_HUMAN (1-678): 6.28e-152: 457: 100.00
+	Hs
		1020856 TRAF2_HUMAN (28-554): 1.19e-102: 320: 31.66		DHX58_HUMAN (1-678): 6.28e-152: 457: 100.00
+	Hs
		1286224 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		DHX58_HUMAN (1-678): 6.28e-152: 457: 100.00
+	Hs
		321891 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		RIGI_HUMAN (1-666): 1.75e-101: 333: 29.89
+	Mm
		761822 TRAF2_MOUSE (28-554): 5.26e-102: 318: 33.46		RIGI_MOUSE (1-666): 3.84e-103: 337: 28.88
+	Mm
		1111925 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		SMCA4_MOUSE (3-592): 1.63e-74: 264: 12.94
+	Hs
		1317601 TRIM7_HUMAN (18-469): 2.35e-60: 209: 11.48		IFIH1_HUMAN (1-674): 7.37e-119: 381: 40.39
+	Hs
		134011 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Mm
		1163172 TRI11_MOUSE (34-468): 3.31e-70: 235: 13.70		RIGI_MOUSE (1-666): 3.84e-103: 337: 28.88
+	Hs
		321931 TRIM7_HUMAN (18-469): 2.35e-60: 209: 11.48		RIGI_HUMAN (1-666): 1.75e-101: 333: 29.89
+	Hs
		536834 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		134263 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		536917 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		FANCM_HUMAN (4-542): 6.34e-65: 235: 17.68
+	Hs
		134128 TRI58_HUMAN (37-469): 5.59e-75: 248: 12.98		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		134009 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		1271706 TRAF6_HUMAN (21-551): 1.31e-81: 266: 22.02		DDX17_HUMAN (2-260): 1.9e-42: 165: 17.23
+	Hs
		571424 TRAF1_HUMAN (161-552): 9.66e-75: 245: 30.00		DDX5_HUMAN (2-255): 1.99e-37: 150: 15.21
+	Hs
		536749 TRI27_HUMAN (32-469): 5.05e-69: 233: 10.97		IF4A3_HUMAN (2-345): 5e-28: 118: 8.96
+	Dm
		580736 Q960H6_DROME (124-550): 9.53e-66: 222: 20.05		DDX17_DROME (335-500): 7.82e-16: 83.3: 22.16
+	Dm
		580763 Q9VXG5_DROME (153-550): 5.24e-61: 208: 19.28		DDX17_DROME (335-500): 7.82e-16: 83.3: 22.16