HitPredict

Interactor 1: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Interactor 2: MD2L2 (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)
Gene: MAD2L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	30154076, 29789392
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 211
+	Hs
		1029303 EHMT2_HUMAN (21-1210): 0: 909: 100.00		MD2L1_HUMAN (4-203): 9.75e-61: 190: 23.04
+	Hs
		1334141 EHMT1_HUMAN (1-1209): 0: 685: 45.63		MD2L2_HUMAN (1-211): 2.72e-87: 258: 100.00
+	Hs
		1029326 EHMT1_HUMAN (1-1209): 0: 685: 45.63		MD2L1_HUMAN (4-203): 9.75e-61: 190: 23.04