HitPredict

Interactor 1: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Interactor 2: EHD2 (Q9NZN4)
EH domain-containing protein 2 (PAST homolog 2)
Gene: EHD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0010008 - endosome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 543
+	Hs
		951410 RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		925677 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		892636 RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		564712 RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		1183545 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		545664 RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		900984 RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		892597 RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		564685 RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		894522 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		545618 RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		925602 RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		1330957 RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		1330916 RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		894411 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		1328986 RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		1078851 RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67
+	Hs
		894047 CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67
+	Zm
		17086 B4FB55_MAIZE (27-234): 1.35e-73: 224: 24.07		A0A1D6GU10_MAIZE (447-523): 2.91e-20: 96.3: 26.92