HitPredict - High confidence protein-protein interactions

Interactor 1: NOX5 (Q96PH1)
NADPH oxidase 5 (EC 1.6.3.-)
Gene: NOX5

Interactor 2: NOX5 (Q96PH1)
NADPH oxidase 5 (EC 1.6.3.-)
Gene: NOX5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	14982937, 21319793
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	EF-hand_5~EF-hand_5, EF-hand_5~EF-hand_6, EF-hand_6~EF-hand_6, FAD_binding_8~FAD_binding_8, FAD_binding_8~Ferric_reduct, FAD_binding_8~NAD_binding_6, Ferric_reduct~Ferric_reduct, NAD_binding_6~NAD_binding_6
Common GO terms	GO:0001525 - angiogenesis GO:0001819 - positive regulation of cytokine production GO:0001935 - endothelial cell proliferation GO:0005509 - calcium ion binding GO:0005783 - endoplasmic reticulum and 16 others more... GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0006952 - defense response GO:0015252 - proton channel activity GO:0016175 - superoxide-generating NAD(P)H oxidase activity GO:0020037 - heme binding GO:0042554 - superoxide anion generation GO:0043012 - regulation of fusion of sperm to egg plasma membrane GO:0043020 - NADPH oxidase complex GO:0050660 - flavin adenine dinucleotide binding GO:0050661 - NADP binding GO:0061640 - cytoskeleton-dependent cytokinesis GO:0106292 - superoxide-generating NADPH oxidase activity GO:1902600 - proton transmembrane transport GO:2000379 - positive regulation of reactive oxygen species metabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	765
Hs

1	765

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Last updated: 15 Jul 2024